Entity Details

Primary name CAN5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO15484
EntryNameCAN5_HUMAN
FullNameCalpain-5
TaxID9606
Evidenceevidence at protein level
Length640
SequenceStatuscomplete
DateCreated2003-02-12
DateModified2021-06-02

Ontological Relatives

GenesCAPN5

GO terms

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GOName
GO:0004198 calcium-dependent cysteine-type endopeptidase activity
GO:0005737 cytoplasm
GO:0005925 focal adhesion
GO:0006508 proteolysis
GO:0007165 signal transduction
GO:0009986 cell surface
GO:0070062 extracellular exosome

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000008 C2 domainDomainDomain
IPR000169 Cysteine peptidase, cysteine active siteSiteActive site
IPR001300 Peptidase C2, calpain, catalytic domainDomainDomain
IPR022682 Peptidase C2, calpain, large subunit, domain IIIDomainDomain
IPR022683 Peptidase C2, calpain, domain IIIDomainDomain
IPR022684 Peptidase C2, calpain familyFamilyFamily
IPR033883 Calpain subdomain IIIDomainDomain
IPR033884 Calpain C2 domainDomainDomain
IPR035892 C2 domain superfamilyFamilyHomologous superfamily
IPR036213 Calpain large subunit, domain III superfamilyFamilyHomologous superfamily
IPR038765 Papain-like cysteine peptidase superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
CAN5_HUMANMLH1_HUMANBioGRID, IntAct20706999 details
CAN5_HUMANFBX7_HUMANBioGRID27503909 details
CAN5_HUMANZO1_HUMANBioGRID30024968 details