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Entity Details
Primary name
NMNA1_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
Q9HAN9
EntryName
NMNA1_HUMAN
FullName
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1
TaxID
9606
Evidence
evidence at protein level
Length
279
SequenceStatus
complete
DateCreated
2003-05-09
DateModified
2021-06-02
Ontological Relatives
Genes
NMNAT1
GO terms
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GO
Name
GO:0000309
nicotinamide-nucleotide adenylyltransferase activity
GO:0004515
nicotinate-nucleotide adenylyltransferase activity
GO:0005524
ATP binding
GO:0005634
nucleus
GO:0005654
nucleoplasm
GO:0005737
cytoplasm
GO:0009165
nucleotide biosynthetic process
GO:0009435
NAD biosynthetic process
GO:0009611
response to wounding
GO:0016604
nuclear body
GO:0019674
NAD metabolic process
GO:0042802
identical protein binding
GO:0043410
positive regulation of MAPK cascade
GO:0043524
negative regulation of neuron apoptotic process
GO:1902511
negative regulation of apoptotic DNA fragmentation
GO:1990966
ATP generation from poly-ADP-D-ribose
Subcellular Location
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Subcellular Location
Nucleus
Domains
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Domain
Name
Category
Type
IPR004821
Cytidyltransferase-like domain
Domain
Domain
IPR005248
Nicotinate/nicotinamide nucleotide adenylyltransferase
Family
Family
Diseases
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Drugs
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Drug
Name
Source
Type
DB03227
Nicotinamide Mononucleotide
Drugbank
small molecule
DB04099
Deamido-Nad+
Drugbank
small molecule
Interactions
22 interactions
Interactor
Partner
Sources
Publications
Link
NMNA1_HUMAN
NMNA1_HUMAN
BioGRID, HPRD, IntAct, MINT
11788603
11959140
21516116
25416956
25502805
31515488
32296183
details
NMNA1_HUMAN
FLOT2_HUMAN
BioGRID, IntAct
21988832
details
NMNA1_HUMAN
MSX1_HUMAN
BioGRID, IntAct
21988832
details
NMNA1_HUMAN
NEK3_HUMAN
BioGRID, IntAct
21988832
details
NMNA1_HUMAN
NTRK2_HUMAN
BioGRID, IntAct
21988832
details
NMNA1_HUMAN
SIK1_HUMAN
BioGRID, IntAct
21988832
details
NMNA1_HUMAN
SIR1_HUMAN
BioGRID, UniProt
19478080
details
NMNA1_HUMAN
CCNC_HUMAN
BioGRID, IntAct
25416956
31515488
details
NMNA1_HUMAN
IMA1_HUMAN
BioGRID, IntAct
25416956
31515488
32296183
details
NMNA1_HUMAN
T23O_HUMAN
BioGRID, IntAct
24722188
32296183
details
NMNA1_HUMAN
BANP_HUMAN
BioGRID, IntAct
26871637
32296183
details
NMNA1_HUMAN
NF2IP_HUMAN
BioGRID, IntAct
32296183
details
NMNA1_HUMAN
PICK1_HUMAN
BioGRID, IntAct
32296183
details
NMNA1_HUMAN
GORS2_HUMAN
BioGRID, IntAct
32296183
details
NMNA1_HUMAN
RNF4_HUMAN
BioGRID, IntAct
32296183
details
NMNA1_HUMAN
IMA5_HUMAN
BioGRID, IntAct
32296183
details
NMNA1_HUMAN
IMA4_HUMAN
BioGRID, IntAct
32296183
details
NMNA1_HUMAN
IMA7_HUMAN
BioGRID, IntAct
32296183
details
NMNA1_HUMAN
PARP1_HUMAN
DIP
17360427
details
NMNA1_HUMAN
A4_HUMAN
BioGRID
21832049
details
NMNA1_HUMAN
IMA6_HUMAN
BioGRID
32296183
details
NMNA1_HUMAN
CDC5L_HUMAN
BioGRID
26186194
29395067
details
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