Entity Details

Primary name IL21_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9HBE4
EntryNameIL21_HUMAN
FullNameInterleukin-21
TaxID9606
Evidenceevidence at protein level
Length162
SequenceStatuscomplete
DateCreated2004-11-23
DateModified2021-06-02

Ontological Relatives

GenesIL21

GO terms

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GOName
GO:0001819 positive regulation of cytokine production
GO:0002314 germinal center B cell differentiation
GO:0002639 positive regulation of immunoglobulin production
GO:0005125 cytokine activity
GO:0005126 cytokine receptor binding
GO:0005134 interleukin-2 receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0007165 signal transduction
GO:0007260 tyrosine phosphorylation of STAT protein
GO:0008284 positive regulation of cell population proliferation
GO:0030890 positive regulation of B cell proliferation
GO:0032729 positive regulation of interferon-gamma production
GO:0032740 positive regulation of interleukin-17 production
GO:0034105 positive regulation of tissue remodeling
GO:0038114 interleukin-21-mediated signaling pathway
GO:0042102 positive regulation of T cell proliferation
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
GO:0045954 positive regulation of natural killer cell mediated cytotoxicity
GO:0048469 cell maturation
GO:0050729 positive regulation of inflammatory response
GO:0051607 defense response to virus
GO:0061470 T follicular helper cell differentiation
GO:0098586 cellular response to virus

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR003443 Interleukin-15/Interleukin-21 familyFamilyFamily
IPR009079 Four-helical cytokine-like, coreFamilyHomologous superfamily

Diseases

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