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Entity Details
Primary name
KDM6A_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
O15550
EntryName
KDM6A_HUMAN
FullName
Lysine-specific demethylase 6A
TaxID
9606
Evidence
evidence at protein level
Length
1401
SequenceStatus
complete
DateCreated
1999-07-15
DateModified
2021-06-02
Ontological Relatives
Genes
KDM6A
GO terms
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GO
Name
GO:0000978
RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0005634
nucleus
GO:0005654
nucleoplasm
GO:0006338
chromatin remodeling
GO:0007507
heart development
GO:0010468
regulation of gene expression
GO:0031490
chromatin DNA binding
GO:0035097
histone methyltransferase complex
GO:0044666
MLL3/4 complex
GO:0046872
metal ion binding
GO:0051213
dioxygenase activity
GO:0051568
histone H3-K4 methylation
GO:0071557
histone H3-K27 demethylation
GO:0071558
histone demethylase activity (H3-K27 specific)
Subcellular Location
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Subcellular Location
Nucleus
Domains
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Domain
Name
Category
Type
IPR003347
JmjC domain
Domain
Domain
IPR011990
Tetratricopeptide-like helical domain superfamily
Family
Homologous superfamily
IPR019734
Tetratricopeptide repeat
Repeat
Repeat
Diseases
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Drugs
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Interactions
35 interactions
Interactor
Partner
Sources
Publications
Link
KDM6A_HUMAN
SMAD9_HUMAN
BioGRID, HPRD, MINT
15231748
details
KDM6A_HUMAN
GSC2_HUMAN
BioGRID, IntAct
32296183
details
KDM6A_HUMAN
TLE1_HUMAN
BioGRID, HPRD
9854018
details
KDM6A_HUMAN
H31T_HUMAN
BioGRID
17761849
details
KDM6A_HUMAN
H31_HUMAN
BioGRID
17713478
details
KDM6A_HUMAN
SRF_HUMAN
BioGRID
22192413
details
KDM6A_HUMAN
TBX5_HUMAN
BioGRID
22192413
details
KDM6A_HUMAN
NKX25_HUMAN
BioGRID
22192413
details
KDM6A_HUMAN
H32_HUMAN
BioGRID
21575637
details
KDM6A_HUMAN
MEOX2_HUMAN
BioGRID
32296183
details
KDM6A_HUMAN
CBP_HUMAN
BioGRID
32238831
details
KDM6A_HUMAN
SIX4_HUMAN
MINT
20300060
details
KDM6A_HUMAN
KMT2D_HUMAN
BioGRID, MINT, UniProt
17178841
17761849
24491801
24981860
29785026
32350066
details
KDM6A_HUMAN
PAXI1_HUMAN
BioGRID, MINT, UniProt
17178841
17500065
17761849
17925232
24981860
29785026
details
KDM6A_HUMAN
RBBP5_HUMAN
BioGRID, MINT, UniProt
17178841
17500065
17761849
17825402
24981860
29785026
31076518
details
KDM6A_HUMAN
ASH2L_HUMAN
BioGRID, MINT, UniProt
17178841
17761849
17825402
20305087
24981860
29785026
31076518
34079125
details
KDM6A_HUMAN
WDR5_HUMAN
BioGRID, IntAct, MINT, UniProt
17178841
17761849
17825402
24981860
26186194
27705803
28514442
29785026
details
KDM6A_HUMAN
NCOA6_HUMAN
BioGRID, DIP, MINT, UniProt
17178841
17761849
19047629
19433796
24981860
29785026
details
KDM6A_HUMAN
SOX2_HUMAN
BioGRID, DIP
22801502
28794006
details
KDM6A_HUMAN
PO5F1_HUMAN
DIP
22801502
details
KDM6A_HUMAN
KLF4_HUMAN
DIP
22801502
details
KDM6A_HUMAN
KMT2C_HUMAN
BioGRID, MINT
17761849
24981860
29785026
details
KDM6A_HUMAN
N4BP2_HUMAN
BioGRID
17761849
details
KDM6A_HUMAN
PP6R3_HUMAN
BioGRID
17761849
details
KDM6A_HUMAN
ZN281_HUMAN
BioGRID
17761849
details
KDM6A_HUMAN
PRSR1_HUMAN
BioGRID
17761849
details
KDM6A_HUMAN
WDR82_HUMAN
BioGRID
20516061
24981860
details
KDM6A_HUMAN
GATA4_HUMAN
BioGRID
22192413
details
KDM6A_HUMAN
SMCA4_HUMAN
BioGRID
22192413
details
KDM6A_HUMAN
P53_HUMAN
BioGRID
24078252
details
KDM6A_HUMAN
MAFA_HUMAN
BioGRID
26180087
details
KDM6A_HUMAN
MAFB_HUMAN
BioGRID
26180087
details
KDM6A_HUMAN
RING2_HUMAN
BioGRID
26450788
details
KDM6A_HUMAN
BAP1_HUMAN
BioGRID
29785026
details
KDM6A_HUMAN
FBXW7_HUMAN
BioGRID
32350066
details
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