Entity Details

Primary name CELR2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9HCU4
EntryNameCELR2_HUMAN
FullNameCadherin EGF LAG seven-pass G-type receptor 2
TaxID9606
Evidenceevidence at protein level
Length2923
SequenceStatuscomplete
DateCreated2002-08-02
DateModified2021-06-02

Ontological Relatives

GenesCELSR2

GO terms

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GOName
GO:0001764 neuron migration
GO:0003341 cilium movement
GO:0004930 G protein-coupled receptor activity
GO:0005509 calcium ion binding
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0006355 regulation of transcription, DNA-templated
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007186 G protein-coupled receptor signaling pathway
GO:0016021 integral component of membrane
GO:0016055 Wnt signaling pathway
GO:0021591 ventricular system development
GO:0021999 neural plate anterior/posterior regionalization
GO:0022407 regulation of cell-cell adhesion
GO:0032880 regulation of protein localization
GO:0033326 cerebrospinal fluid secretion
GO:0048813 dendrite morphogenesis
GO:0060071 Wnt signaling pathway, planar cell polarity pathway
GO:0060271 cilium assembly
GO:0098609 cell-cell adhesion

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000152 EGF-type aspartate/asparagine hydroxylation sitePTMPTM
IPR000203 GPS motifDomainDomain
IPR000742 EGF-like domainDomainDomain
IPR000832 GPCR, family 2, secretin-likeFamilyFamily
IPR001791 Laminin G domainDomainDomain
IPR001879 GPCR, family 2, extracellular hormone receptor domainDomainDomain
IPR001881 EGF-like calcium-binding domainDomainDomain
IPR002049 Laminin EGF domainDomainDomain
IPR002126 Cadherin-likeDomainDomain
IPR009030 Growth factor receptor cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR013032 EGF-like, conserved siteSiteConserved site
IPR013320 Concanavalin A-like lectin/glucanase domain superfamilyFamilyHomologous superfamily
IPR015919 Cadherin-like superfamilyFamilyHomologous superfamily
IPR017981 GPCR, family 2-likeDomainDomain
IPR020894 Cadherin conserved siteSiteConserved site
IPR032471 GAIN domain, N-terminalDomainDomain
IPR036445 GPCR family 2, extracellular hormone receptor domain superfamilyFamilyHomologous superfamily

Diseases

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