Entity Details

Primary name TMPS4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NRS4
EntryNameTMPS4_HUMAN
FullNameTransmembrane protease serine 4
TaxID9606
Evidenceevidence at protein level
Length437
SequenceStatuscomplete
DateCreated2001-04-27
DateModified2021-06-02

Ontological Relatives

GenesTMPRSS4

GO terms

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GOName
GO:0004252 serine-type endopeptidase activity
GO:0005044 scavenger receptor activity
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0006508 proteolysis
GO:0008236 serine-type peptidase activity
GO:0009611 response to wounding
GO:0010468 regulation of gene expression
GO:0016021 integral component of membrane
GO:0016485 protein processing
GO:0030141 secretory granule
GO:0045967 negative regulation of growth rate
GO:0046598 positive regulation of viral entry into host cell

Subcellular Location

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Subcellular Location
Cell membrane
Secreted

Domains

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DomainNameCategoryType
IPR001190 SRCR domainDomainDomain
IPR001254 Serine proteases, trypsin domainDomainDomain
IPR001314 Peptidase S1A, chymotrypsin familyFamilyFamily
IPR002172 Low-density lipoprotein (LDL) receptor class A repeatRepeatRepeat
IPR009003 Peptidase S1, PA clanFamilyHomologous superfamily
IPR017448 SRCR-like domainDomainDomain
IPR018114 Serine proteases, trypsin family, histidine active siteSiteActive site
IPR033116 Serine proteases, trypsin family, serine active siteSiteActive site
IPR036055 LDL receptor-like superfamilyFamilyHomologous superfamily
IPR036772 SRCR-like domain superfamilyFamilyHomologous superfamily
IPR043504 Peptidase S1, PA clan, chymotrypsin-like foldFamilyHomologous superfamily

Diseases

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