Entity Details

Primary name DDX18_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NVP1
EntryNameDDX18_HUMAN
FullNameATP-dependent RNA helicase DDX18
TaxID9606
Evidenceevidence at protein level
Length670
SequenceStatuscomplete
DateCreated2001-02-21
DateModified2021-06-02

Ontological Relatives

GenesDDX18

GO terms

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GOName
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0005524 ATP binding
GO:0005694 chromosome
GO:0005730 nucleolus
GO:0016020 membrane
GO:0071392 cellular response to estradiol stimulus

Subcellular Location

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Subcellular Location
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR000629 ATP-dependent RNA helicase DEAD-box, conserved siteSiteConserved site
IPR001650 Helicase, C-terminalDomainDomain
IPR011545 DEAD/DEAH box helicase domainDomainDomain
IPR014001 Helicase superfamily 1/2, ATP-binding domainDomainDomain
IPR014014 RNA helicase, DEAD-box type, Q motifDomainDomain
IPR025313 Domain of unknown function DUF4217DomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily

Diseases

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