Entity Details

Primary name NLE1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NVX2
EntryNameNLE1_HUMAN
FullNameNotchless protein homolog 1
TaxID9606
Evidenceevidence at protein level
Length485
SequenceStatuscomplete
DateCreated2003-09-19
DateModified2021-06-02

Ontological Relatives

GenesNLE1

GO terms

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GOName
GO:0000027 ribosomal large subunit assembly
GO:0001756 somitogenesis
GO:0001822 kidney development
GO:0001826 inner cell mass cell differentiation
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0007219 Notch signaling pathway
GO:0045930 negative regulation of mitotic cell cycle
GO:0048705 skeletal system morphogenesis
GO:0061484 hematopoietic stem cell homeostasis
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001632 G-protein, beta subunitDomainDomain
IPR001680 WD40 repeatRepeatRepeat
IPR012972 NLEDomainDomain
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR019775 WD40 repeat, conserved siteSiteConserved site
IPR020472 G-protein beta WD-40 repeatRepeatRepeat
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

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