Entity Details

Primary name DACH1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UI36
EntryNameDACH1_HUMAN
FullNameDachshund homolog 1
TaxID9606
Evidenceevidence at protein level
Length758
SequenceStatuscomplete
DateCreated2004-03-01
DateModified2021-06-02

Ontological Relatives

GenesDACH1

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001967 suckling behavior
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007585 respiratory gaseous exchange by respiratory system
GO:0008283 cell population proliferation
GO:0010944 negative regulation of transcription by competitive promoter binding
GO:0030336 negative regulation of cell migration
GO:0033262 regulation of nuclear cell cycle DNA replication
GO:0045892 negative regulation of transcription, DNA-templated
GO:0046545 development of primary female sexual characteristics
GO:0048147 negative regulation of fibroblast proliferation
GO:0060244 negative regulation of cell proliferation involved in contact inhibition
GO:2000279 negative regulation of DNA biosynthetic process

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR003380 SKI/SNO/DAC domainDomainDomain
IPR009061 Putative DNA-binding domain superfamilyFamilyHomologous superfamily
IPR037000 Ski-like, DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

42 interactions

InteractorPartnerSourcesPublicationsLink
DACH1_HUMANSMAD4_HUMANBioGRID, HPRD, UniProt14525983 details
DACH1_HUMANUBC9_HUMANBioGRID, HPRD, IntAct11025202 16189514 details
DACH1_HUMANNAGK_HUMANBioGRID, HPRD, IntAct, MINT16189514 21516116 25416956 32296183 details
DACH1_HUMANSAHH2_HUMANBioGRID, IntAct25416956 32296183 details
DACH1_HUMANU2AF2_HUMANBioGRID, IntAct25416956 details
DACH1_HUMANFGF12_HUMANBioGRID, IntAct25416956 32296183 details
DACH1_HUMANPPIG_HUMANBioGRID, IntAct25416956 details
DACH1_HUMANZCH10_HUMANBioGRID, IntAct25416956 details
DACH1_HUMANMMTA2_HUMANBioGRID, IntAct21516116 25416956 details
DACH1_HUMANRNF14_HUMANBioGRID, IntAct25416956 32296183 details
DACH1_HUMANDACH1_HUMANBioGRID, IntAct25416956 28205554 details
DACH1_HUMANJUN_HUMANBioGRID, MINT16980615 17182846 25609649 details
DACH1_HUMANKAP1_HUMANBioGRID, IntAct32296183 details
DACH1_HUMANSRS11_HUMANBioGRID, IntAct32296183 details
DACH1_HUMANFOXO1_HUMANBioGRID28205554 details
DACH1_HUMANMYC_HUMANBioGRID28205554 details
DACH1_HUMANSOX3_HUMANBioGRID28205554 details
DACH1_HUMANTEAD2_HUMANBioGRID28205554 details
DACH1_HUMANSOX4_HUMANBioGRID28205554 details
DACH1_HUMANAURKA_HUMANBioGRID28205554 details
DACH1_HUMANMERL_HUMANBioGRID28205554 details
DACH1_HUMANSTK11_HUMANBioGRID28205554 details
DACH1_HUMANTFE2_HUMANBioGRID28205554 details
DACH1_HUMANTERT_HUMANBioGRID28205554 details
DACH1_HUMANNFIC_HUMANBioGRID28205554 details
DACH1_HUMANSMAD1_HUMANBioGRID28205554 details
DACH1_HUMANEYA1_HUMANHPRD11950062 details
DACH1_HUMANSMAD3_HUMANBioGRID, HPRD, UniProt14525983 details
DACH1_HUMANSIN3A_HUMANBioGRID, HPRD, UniProt14525983 details
DACH1_HUMANNCOR1_HUMANBioGRID, HPRD, UniProt14525983 17182846 details
DACH1_HUMANHDAC1_HUMANBioGRID17182846 details
DACH1_HUMANHDAC3_HUMANBioGRID17182846 details
DACH1_HUMANCREB1_HUMANBioGRID16980615 details
DACH1_HUMANP53_HUMANBioGRID23798621 details
DACH1_HUMANNXF1_HUMANBioGRID29395067 details
DACH1_HUMANSMG7_HUMANBioGRID29395067 details
DACH1_HUMANCPSF1_HUMANBioGRID29395067 details
DACH1_HUMANIF4A3_HUMANBioGRID29395067 details
DACH1_HUMANPARN_HUMANBioGRID29395067 details
DACH1_HUMANSIX1_HUMANHPRD14628042 details
DACH1_HUMANEYA3_HUMANHPRD14628042 details
DACH1_HUMANCBP_HUMANHPRD12215533 details