Entity Details

Primary name INO80_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9ULG1
EntryNameINO80_HUMAN
FullNameChromatin-remodeling ATPase INO80
TaxID9606
Evidenceevidence at protein level
Length1556
SequenceStatuscomplete
DateCreated2006-09-05
DateModified2021-06-02

Ontological Relatives

GenesINO80

GO terms

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GOName
GO:0000070 mitotic sister chromatid segregation
GO:0000724 double-strand break repair via homologous recombination
GO:0003677 DNA binding
GO:0003779 actin binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005819 spindle
GO:0005829 cytosol
GO:0005874 microtubule
GO:0006281 DNA repair
GO:0006302 double-strand break repair
GO:0006338 chromatin remodeling
GO:0006351 transcription, DNA-templated
GO:0008094 ATPase, acting on DNA
GO:0010571 positive regulation of nuclear cell cycle DNA replication
GO:0016579 protein deubiquitination
GO:0016604 nuclear body
GO:0016887 ATP hydrolysis activity
GO:0030307 positive regulation of cell growth
GO:0031011 Ino80 complex
GO:0032508 DNA duplex unwinding
GO:0034644 cellular response to UV
GO:0042393 histone binding
GO:0042766 nucleosome mobilization
GO:0043014 alpha-tubulin binding
GO:0043044 ATP-dependent chromatin remodeling
GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0051225 spindle assembly
GO:0051301 cell division
GO:0070615 nucleosome-dependent ATPase activity
GO:0070914 UV-damage excision repair
GO:0071479 cellular response to ionizing radiation
GO:2000045 regulation of G1/S transition of mitotic cell cycle

Subcellular Location

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Subcellular Location
Chromosome
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000330 SNF2, N-terminalDomainDomain
IPR001650 Helicase, C-terminalDomainDomain
IPR014001 Helicase superfamily 1/2, ATP-binding domainDomainDomain
IPR020838 DBINO domainDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR031047 DNA helicase Ino80FamilyFamily
IPR038718 SNF2-like, N-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

24 interactions

InteractorPartnerSourcesPublicationsLink
INO80_HUMANTYY1_HUMANBioGRID, IntAct, MINT, UniProt17721549 18026119 21303910 24981860 27705803 details
INO80_HUMANPKHF2_HUMANBioGRID, IntAct32296183 details
INO80_HUMANACTN4_HUMANBioGRID20197409 details
INO80_HUMANRUVB1_HUMANBioGRID, IntAct16230350 17721549 21303910 22939629 28514442 details
INO80_HUMANRUVB2_HUMANBioGRID, IntAct16230350 17721549 21303910 28514442 28561026 details
INO80_HUMANIN80B_HUMANBioGRID, IntAct16230350 17721549 21303910 28561026 details
INO80_HUMANARP8_HUMANBioGRID, IntAct16230350 17721549 21303910 22939629 24981860 details
INO80_HUMANACL6A_HUMANBioGRID, IntAct, UniProt16230350 18026119 21303910 details
INO80_HUMANMCRS1_HUMANBioGRID, IntAct16230350 17721549 21303910 24981860 details
INO80_HUMANIN80E_HUMANBioGRID, IntAct, UniProt16230350 17721549 18922472 21303910 24981860 26344197 details
INO80_HUMANIN80D_HUMANBioGRID, IntAct16230350 17721549 21303910 24981860 details
INO80_HUMANH2AX_HUMANUniProt19014934 details
INO80_HUMANARP5_HUMANBioGRID, DIP, IntAct, UniProt17721549 19014934 20197409 20855601 21303910 26344197 26496610 29643506 details
INO80_HUMANUCHL5_HUMANBioGRID, IntAct, UniProt18922472 21303910 24981860 26186194 28514442 28598414 details
INO80_HUMANPARP1_HUMANMINT24145797 details
INO80_HUMANDDB1_HUMANBioGRID, DIP20855601 details
INO80_HUMANACTB_HUMANBioGRID20197409 details
INO80_HUMANIN80C_HUMANBioGRID17721549 21303910 22939629 details
INO80_HUMANNFRKB_HUMANBioGRID17721549 21303910 22939629 24981860 25194926 26344197 details
INO80_HUMANTFPT_HUMANBioGRID17721549 21303910 24981860 details
INO80_HUMANTBA1B_HUMANBioGRID20237820 details
INO80_HUMANTBA1A_HUMANBioGRID22133677 details
INO80_HUMANBAP1_HUMANBioGRID25283999 31657441 details
INO80_HUMANH2A2C_HUMANBioGRID25283999 details