Entity Details

Primary name HEG1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9ULI3
EntryNameHEG1_HUMAN
FullNameProtein HEG homolog 1
TaxID9606
Evidenceevidence at protein level
Length1381
SequenceStatuscomplete
DateCreated2007-05-15
DateModified2021-06-02

Ontological Relatives

GenesHEG1

GO terms

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GOName
GO:0001570 vasculogenesis
GO:0001701 in utero embryonic development
GO:0001886 endothelial cell morphogenesis
GO:0001945 lymph vessel development
GO:0003017 lymph circulation
GO:0003209 cardiac atrium morphogenesis
GO:0003222 ventricular trabecula myocardium morphogenesis
GO:0003281 ventricular septum development
GO:0005509 calcium ion binding
GO:0005576 extracellular region
GO:0005911 cell-cell junction
GO:0007043 cell-cell junction assembly
GO:0007507 heart development
GO:0009791 post-embryonic development
GO:0009897 external side of plasma membrane
GO:0016021 integral component of membrane
GO:0030324 lung development
GO:0035024 negative regulation of Rho protein signal transduction
GO:0035264 multicellular organism growth
GO:0048845 venous blood vessel morphogenesis
GO:0050878 regulation of body fluid levels
GO:0055017 cardiac muscle tissue growth
GO:0060039 pericardium development
GO:0090271 positive regulation of fibroblast growth factor production
GO:1902414 protein localization to cell junction
GO:1905709 negative regulation of membrane permeability
GO:2000299 negative regulation of Rho-dependent protein serine/threonine kinase activity

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Secreted

Domains

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DomainNameCategoryType
IPR000152 EGF-type aspartate/asparagine hydroxylation sitePTMPTM
IPR000742 EGF-like domainDomainDomain
IPR001881 EGF-like calcium-binding domainDomainDomain
IPR018097 EGF-like calcium-binding, conserved siteSiteConserved site
IPR028720 Protein HEGFamilyFamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
HEG1_HUMANKRIT1_HUMANBioGRID, IntAct23007647 28514442 details