Entity Details

Primary name VPP2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y487
EntryNameVPP2_HUMAN
FullNameV-type proton ATPase 116 kDa subunit a2
TaxID9606
Evidenceevidence at protein level
Length856
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesATP6V0A2

GO terms

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GOName
GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain
GO:0001669 acrosomal vesicle
GO:0005765 lysosomal membrane
GO:0005886 plasma membrane
GO:0006879 cellular iron ion homeostasis
GO:0006955 immune response
GO:0007035 vacuolar acidification
GO:0008286 insulin receptor signaling pathway
GO:0010008 endosome membrane
GO:0016021 integral component of membrane
GO:0016241 regulation of macroautophagy
GO:0016471 vacuolar proton-transporting V-type ATPase complex
GO:0030670 phagocytic vesicle membrane
GO:0033572 transferrin transport
GO:0034220 ion transmembrane transport
GO:0036295 cellular response to increased oxygen levels
GO:0046961 proton-transporting ATPase activity, rotational mechanism
GO:0048471 perinuclear region of cytoplasm
GO:0051117 ATPase binding
GO:0090383 phagosome acidification

Subcellular Location

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Subcellular Location
Cell membrane
Endosome membrane

Domains

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DomainNameCategoryType
IPR002490 V-type ATPase, V0 complex, 116kDa subunit familyFamilyFamily
IPR026028 ATPase, V0 complex, subunit 116kDa, eukaryoticFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB01133 Tiludronic acidDrugbanksmall molecule

Interactions

5 interactions