Entity Details

Primary name ADCY3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO60266
EntryNameADCY3_HUMAN
FullNameAdenylate cyclase type 3
TaxID9606
Evidenceevidence at protein level
Length1144
SequenceStatuscomplete
DateCreated2001-04-27
DateModified2021-06-02

Ontological Relatives

GenesADCY3

GO terms

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GOName
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0003091 renal water homeostasis
GO:0004016 adenylate cyclase activity
GO:0005516 calmodulin binding
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005929 cilium
GO:0006171 cAMP biosynthetic process
GO:0007165 signal transduction
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007190 activation of adenylate cyclase activity
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO:0007338 single fertilization
GO:0007340 acrosome reaction
GO:0007608 sensory perception of smell
GO:0008355 olfactory learning
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030317 flagellated sperm motility
GO:0034199 activation of protein kinase A activity
GO:0035556 intracellular signal transduction
GO:0046872 metal ion binding
GO:0071377 cellular response to glucagon stimulus
GO:1904322 cellular response to forskolin

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection
Cytoplasm
Golgi apparatus

Domains

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DomainNameCategoryType
IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclaseDomainDomain
IPR018297 Adenylyl cyclase class-4/guanylyl cyclase, conserved siteSiteConserved site
IPR029787 Nucleotide cyclaseFamilyHomologous superfamily
IPR030672 Adenylate cyclaseFamilyFamily
IPR032628 Adenylate cyclase, N-terminalDomainDomain

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
ADCY3_HUMANMTR1B_HUMANBioGRID, IntAct26514267 details
ADCY3_HUMANADRB2_HUMANBioGRID24561123 details
ADCY3_HUMANSTML3_HUMANHPRD12122055 details