Entity Details

Primary name SLIT3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO75094
EntryNameSLIT3_HUMAN
FullNameSlit homolog 3 protein
TaxID9606
Evidenceevidence at transcript level
Length1523
SequenceStatuscomplete
DateCreated2004-03-15
DateModified2021-06-02

Ontological Relatives

GenesSLIT3

GO terms

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GOName
GO:0003180 aortic valve morphogenesis
GO:0003181 atrioventricular valve morphogenesis
GO:0005509 calcium ion binding
GO:0005615 extracellular space
GO:0005739 mitochondrion
GO:0007411 axon guidance
GO:0008201 heparin binding
GO:0008285 negative regulation of cell population proliferation
GO:0010629 negative regulation of gene expression
GO:0030308 negative regulation of cell growth
GO:0032870 cellular response to hormone stimulus
GO:0035385 Roundabout signaling pathway
GO:0048495 Roundabout binding
GO:0048846 axon extension involved in axon guidance
GO:0050919 negative chemotaxis
GO:0051414 response to cortisol
GO:0060412 ventricular septum morphogenesis
GO:0061364 apoptotic process involved in luteolysis
GO:0070100 negative regulation of chemokine-mediated signaling pathway

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000152 EGF-type aspartate/asparagine hydroxylation sitePTMPTM
IPR000372 Leucine-rich repeat N-terminal domainDomainDomain
IPR000483 Cysteine-rich flanking region, C-terminalDomainDomain
IPR000742 EGF-like domainDomainDomain
IPR001611 Leucine-rich repeatRepeatRepeat
IPR001791 Laminin G domainDomainDomain
IPR001881 EGF-like calcium-binding domainDomainDomain
IPR003591 Leucine-rich repeat, typical subtypeRepeatRepeat
IPR006207 Cystine knot, C-terminalDomainDomain
IPR009030 Growth factor receptor cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR013032 EGF-like, conserved siteSiteConserved site
IPR013320 Concanavalin A-like lectin/glucanase domain superfamilyFamilyHomologous superfamily
IPR018097 EGF-like calcium-binding, conserved siteSiteConserved site
IPR032675 Leucine-rich repeat domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
SLIT3_HUMANCAN1_HUMANBioGRID, HPRD12358155 details
SLIT3_HUMANROBO2_HUMANHPRD11754167 details