Entity Details

Primary name ADAP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO75689
EntryNameADAP1_HUMAN
FullNameArf-GAP with dual PH domain-containing protein 1
TaxID9606
Evidenceevidence at protein level
Length374
SequenceStatuscomplete
DateCreated2005-07-05
DateModified2021-06-02

Ontological Relatives

GenesADAP1

GO terms

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GOName
GO:0005096 GTPase activator activity
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007166 cell surface receptor signaling pathway
GO:0043087 regulation of GTPase activity
GO:0043231 intracellular membrane-bounded organelle
GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding
GO:0046872 metal ion binding
GO:1902936 phosphatidylinositol bisphosphate binding

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001164 Arf GTPase activating proteinDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR037278 ARFGAP/RecO-like zinc fingerFamilyHomologous superfamily
IPR037849 ADAP, PH domain 1DomainDomain
IPR037851 ADAP, PH domain 2DomainDomain
IPR038508 ArfGAP domain superfamilyFamilyHomologous superfamily

Diseases

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