Entity Details

Primary name PR15A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO75807
EntryNamePR15A_HUMAN
FullNameProtein phosphatase 1 regulatory subunit 15A
TaxID9606
Evidenceevidence at protein level
Length674
SequenceStatuscomplete
DateCreated2008-02-26
DateModified2021-06-02

Ontological Relatives

GenesPPP1R15A

GO terms

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GOName
GO:0000164 protein phosphatase type 1 complex
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0006915 apoptotic process
GO:0006974 cellular response to DNA damage stimulus
GO:0008157 protein phosphatase 1 binding
GO:0016020 membrane
GO:0019888 protein phosphatase regulator activity
GO:0019901 protein kinase binding
GO:0032058 positive regulation of translational initiation in response to stress
GO:0032515 negative regulation of phosphoprotein phosphatase activity
GO:0032516 positive regulation of phosphoprotein phosphatase activity
GO:0034976 response to endoplasmic reticulum stress
GO:0035308 negative regulation of protein dephosphorylation
GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation
GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0070972 protein localization to endoplasmic reticulum
GO:0072542 protein phosphatase activator activity
GO:1902310 positive regulation of peptidyl-serine dephosphorylation
GO:1903898 negative regulation of PERK-mediated unfolded protein response
GO:1903917 positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane
Mitochondrion outer membrane

Domains

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DomainNameCategoryType
IPR019523 Protein phosphatase 1, regulatory subunit 15A/B, C-terminalDomainDomain

Diseases

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