Entity Details

Primary name LRIG2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO94898
EntryNameLRIG2_HUMAN
FullNameLeucine-rich repeats and immunoglobulin-like domains protein 2
TaxID9606
Evidenceevidence at protein level
Length1065
SequenceStatuscomplete
DateCreated2004-10-11
DateModified2021-06-02

Ontological Relatives

GenesLRIG2

GO terms

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GOName
GO:0005102 signaling receptor binding
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0007605 sensory perception of sound
GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway
GO:0016021 integral component of membrane
GO:0030426 growth cone
GO:0031012 extracellular matrix
GO:0043025 neuronal cell body
GO:0048681 negative regulation of axon regeneration
GO:0051045 negative regulation of membrane protein ectodomain proteolysis
GO:0060384 innervation
GO:0097708 intracellular vesicle
GO:2000010 positive regulation of protein localization to cell surface
GO:2001222 regulation of neuron migration

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm

Domains

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DomainNameCategoryType
IPR000483 Cysteine-rich flanking region, C-terminalDomainDomain
IPR001611 Leucine-rich repeatRepeatRepeat
IPR003591 Leucine-rich repeat, typical subtypeRepeatRepeat
IPR003598 Immunoglobulin subtype 2DomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013098 Immunoglobulin I-setDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR032675 Leucine-rich repeat domain superfamilyFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
LRIG2_HUMANPGFRB_HUMANIntAct30015847 details
LRIG2_HUMANEGFR_HUMANBioGRID, IntAct25353163 details
LRIG2_HUMANST7_HUMANBioGRID29395067 details