Entity Details

Primary name ADCY5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95622
EntryNameADCY5_HUMAN
FullNameAdenylate cyclase type 5
TaxID9606
Evidenceevidence at protein level
Length1261
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesADCY5

GO terms

Show/Hide Table
GOName
GO:0001973 G protein-coupled adenosine receptor signaling pathway
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0003091 renal water homeostasis
GO:0004016 adenylate cyclase activity
GO:0005524 ATP binding
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005929 cilium
GO:0006171 cAMP biosynthetic process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007190 activation of adenylate cyclase activity
GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007626 locomotory behavior
GO:0008179 adenylate cyclase binding
GO:0016021 integral component of membrane
GO:0034199 activation of protein kinase A activity
GO:0035556 intracellular signal transduction
GO:0045111 intermediate filament cytoskeleton
GO:0046872 metal ion binding
GO:0050885 neuromuscular process controlling balance
GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0071377 cellular response to glucagon stimulus
GO:0097110 scaffold protein binding
GO:1904322 cellular response to forskolin

Subcellular Location

Show/Hide Table
Subcellular Location
Cell membrane
Cell projection

Domains

Show/Hide Table
DomainNameCategoryType
IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclaseDomainDomain
IPR009398 Adenylate cyclase, conserved domainDomainDomain
IPR018297 Adenylyl cyclase class-4/guanylyl cyclase, conserved siteSiteConserved site
IPR029787 Nucleotide cyclaseFamilyHomologous superfamily
IPR030672 Adenylate cyclaseFamilyFamily
IPR032628 Adenylate cyclase, N-terminalDomainDomain

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB02587 ColforsinDrugbanksmall molecule
DB06843 2',5'-DIDEOXY-ADENOSINE 3'-MONOPHOSPHATEDrugbanksmall molecule
DB09121 AurothioglucoseDrugbanksmall molecule