Entity Details

Primary name LGI1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95970
EntryNameLGI1_HUMAN
FullNameLeucine-rich glioma-inactivated protein 1
TaxID9606
Evidenceevidence at protein level
Length557
SequenceStatuscomplete
DateCreated2003-07-03
DateModified2021-06-02

Ontological Relatives

GenesLGI1

GO terms

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GOName
GO:0005102 signaling receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0007399 nervous system development
GO:0007411 axon guidance
GO:0030307 positive regulation of cell growth
GO:0031175 neuron projection development
GO:0043083 synaptic cleft
GO:0050806 positive regulation of synaptic transmission
GO:0098978 glutamatergic synapse
GO:0099645 neurotransmitter receptor localization to postsynaptic specialization membrane

Subcellular Location

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Subcellular Location
Cell junction
Secreted

Domains

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DomainNameCategoryType
IPR000483 Cysteine-rich flanking region, C-terminalDomainDomain
IPR001611 Leucine-rich repeatRepeatRepeat
IPR003591 Leucine-rich repeat, typical subtypeRepeatRepeat
IPR005492 Leucine-rich glioma-inactivated , EPTP repeatRepeatRepeat
IPR009039 EARRepeatRepeat
IPR032675 Leucine-rich repeat domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
LGI1_HUMANDLG4_HUMANBioGRID16990550 details
LGI1_HUMANADA22_HUMANBioGRID, HPRD16990550 details