Entity Details

Primary name PERT_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP07202
EntryNamePERT_HUMAN
FullNameThyroid peroxidase
TaxID9606
Evidenceevidence at protein level
Length933
SequenceStatuscomplete
DateCreated1988-04-01
DateModified2021-06-02

Ontological Relatives

GenesTPO

GO terms

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GOName
GO:0004447 iodide peroxidase activity
GO:0004601 peroxidase activity
GO:0005509 calcium ion binding
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006590 thyroid hormone generation
GO:0006979 response to oxidative stress
GO:0009986 cell surface
GO:0020037 heme binding
GO:0035162 embryonic hemopoiesis
GO:0042446 hormone biosynthetic process
GO:0042744 hydrogen peroxide catabolic process

Subcellular Location

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Subcellular Location
Cell surface
Membrane

Domains

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DomainNameCategoryType
IPR000152 EGF-type aspartate/asparagine hydroxylation sitePTMPTM
IPR000436 Sushi/SCR/CCP domainDomainDomain
IPR000742 EGF-like domainDomainDomain
IPR001881 EGF-like calcium-binding domainDomainDomain
IPR010255 Haem peroxidase superfamilyFamilyHomologous superfamily
IPR018097 EGF-like calcium-binding, conserved siteSiteConserved site
IPR019791 Haem peroxidase, animal-typeFamilyFamily
IPR029589 Thyroid peroxidaseFamilyFamily
IPR035976 Sushi/SCR/CCP superfamilyFamilyHomologous superfamily
IPR037120 Haem peroxidase domain superfamily, animal typeFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00389 CarbimazoleDrugbanksmall molecule
DB00509 DextrothyroxineDrugbanksmall molecule
DB00550 PropylthiouracilDrugbanksmall molecule
DB00763 MethimazoleDrugbanksmall molecule
DB05382 IodineDrugbanksmall molecule
DB08604 TriclosanDrugbanksmall molecule
DB11085 ResorcinolDrugbanksmall molecule
DB11496 2-mercaptobenzothiazoleDrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
PERT_HUMANTXD11_HUMANHPRD15561711 details
PERT_HUMANDUOX1_HUMANHPRD15561711 details