Entity Details

Primary name EGR2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP11161
EntryNameEGR2_HUMAN
FullNameE3 SUMO-protein ligase EGR2
TaxID9606
Evidenceevidence at protein level
Length476
SequenceStatuscomplete
DateCreated1989-07-01
DateModified2021-06-02

Ontological Relatives

GenesEGR2

GO terms

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GOName
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003682 chromatin binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006611 protein export from nucleus
GO:0007399 nervous system development
GO:0007420 brain development
GO:0007422 peripheral nervous system development
GO:0007611 learning or memory
GO:0007622 rhythmic behavior
GO:0008045 motor neuron axon guidance
GO:0010467 gene expression
GO:0014037 Schwann cell differentiation
GO:0014040 positive regulation of Schwann cell differentiation
GO:0016925 protein sumoylation
GO:0021612 facial nerve structural organization
GO:0021659 rhombomere 3 structural organization
GO:0021660 rhombomere 3 formation
GO:0021665 rhombomere 5 structural organization
GO:0021666 rhombomere 5 formation
GO:0030278 regulation of ossification
GO:0031625 ubiquitin protein ligase binding
GO:0031643 positive regulation of myelination
GO:0032868 response to insulin
GO:0035284 brain segmentation
GO:0035914 skeletal muscle cell differentiation
GO:0042552 myelination
GO:0043231 intracellular membrane-bounded organelle
GO:0043565 sequence-specific DNA binding
GO:0045444 fat cell differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0048168 regulation of neuronal synaptic plasticity
GO:0061665 SUMO ligase activity
GO:0071310 cellular response to organic substance
GO:0071837 HMG box domain binding
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR013087 Zinc finger C2H2-typeDomainDomain
IPR021849 Early growth response, N-terminalDomainDomain
IPR036236 Zinc finger C2H2 superfamilyFamilyHomologous superfamily

Diseases

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