Entity Details

Primary name ADT1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP12235
EntryNameADT1_HUMAN
FullNameADP/ATP translocase 1
TaxID9606
Evidenceevidence at protein level
Length298
SequenceStatuscomplete
DateCreated1989-10-01
DateModified2021-06-02

Ontological Relatives

GenesSLC25A4

GO terms

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GOName
GO:0000002 mitochondrial genome maintenance
GO:0005471 ATP:ADP antiporter activity
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005757 mitochondrial permeability transition pore complex
GO:0005887 integral component of plasma membrane
GO:0006091 generation of precursor metabolites and energy
GO:0008637 apoptotic mitochondrial changes
GO:0015078 proton transmembrane transporter activity
GO:0015207 adenine transmembrane transporter activity
GO:0015866 ADP transport
GO:0016020 membrane
GO:0016032 viral process
GO:0017077 oxidative phosphorylation uncoupler activity
GO:0032592 integral component of mitochondrial membrane
GO:0046902 regulation of mitochondrial membrane permeability
GO:0060546 negative regulation of necroptotic process
GO:0140021 mitochondrial ADP transmembrane transport
GO:1901526 positive regulation of mitophagy
GO:1990544 mitochondrial ATP transmembrane transport
GO:1990845 adaptive thermogenesis

Subcellular Location

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Subcellular Location
Membrane
Mitochondrion inner membrane

Domains

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DomainNameCategoryType
IPR002067 Mitochondrial carrier proteinFamilyFamily
IPR002113 ADP/ATP carrier protein, eukaryotic typeFamilyFamily
IPR018108 Mitochondrial substrate/solute carrierRepeatRepeat
IPR023395 Mitochondrial carrier domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00171 ATPDrugbanksmall molecule
DB00720 Clodronic acidDrugbanksmall molecule
DB01077 Etidronic acidDrugbanksmall molecule
DB01736 [3-(Dodecanoylamino)Propyl](Hydroxy)DimethylammoniumDrugbanksmall molecule
DB02426 CarboxyatractylosideDrugbanksmall molecule
DB03429 Tetrastearoyl cardiolipinDrugbanksmall molecule
DB04178 Di-Stearoyl-3-Sn-PhosphatidylcholineDrugbanksmall molecule