Entity Details

Primary name HXB4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP17483
EntryNameHXB4_HUMAN
FullNameHomeobox protein Hox-B4
TaxID9606
Evidenceevidence at protein level
Length251
SequenceStatuscomplete
DateCreated1990-08-01
DateModified2021-06-02

Ontological Relatives

GenesHOXB4

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0002011 morphogenesis of an epithelial sheet
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005813 centrosome
GO:0006357 regulation of transcription by RNA polymerase II
GO:0008283 cell population proliferation
GO:0009952 anterior/posterior pattern specification
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048103 somatic stem cell division
GO:0048536 spleen development
GO:0048539 bone marrow development
GO:0048704 embryonic skeletal system morphogenesis
GO:0060216 definitive hemopoiesis
GO:0060218 hematopoietic stem cell differentiation
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000738 positive regulation of stem cell differentiation

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001356 Homeobox domainDomainDomain
IPR001827 Homeobox protein, antennapedia type, conserved siteSiteConserved site
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017970 Homeobox, conserved siteSiteConserved site
IPR017995 Homeobox protein, antennapedia typeFamilyFamily
IPR020479 Homeobox domain, metazoaDomainDomain

Diseases

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