Entity Details

Primary name CNRG_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP18545
EntryNameCNRG_HUMAN
FullNameRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
TaxID9606
Evidenceevidence at protein level
Length87
SequenceStatuscomplete
DateCreated1990-11-01
DateModified2021-06-02

Ontological Relatives

GenesPDE6G

GO terms

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GOName
GO:0000187 obsolete activation of MAPK activity
GO:0004857 enzyme inhibitor activity
GO:0005886 plasma membrane
GO:0007223 Wnt signaling pathway, calcium modulating pathway
GO:0007601 visual perception
GO:0016056 rhodopsin mediated signaling pathway
GO:0022400 regulation of rhodopsin mediated signaling pathway
GO:0030507 spectrin binding
GO:0030553 cGMP binding
GO:0042622 photoreceptor outer segment membrane
GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway
GO:0045745 positive regulation of G protein-coupled receptor signaling pathway
GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity
GO:0097381 photoreceptor disc membrane

Subcellular Location

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Domains

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DomainNameCategoryType
IPR006952 Retinal cGMP phosphodiesterase, gamma subunitFamilyFamily
IPR037030 Retinal cGMP phosphodiesterase, gamma subunit superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00203 SildenafilDrugbanksmall molecule
DB00862 VardenafilDrugbanksmall molecule
DB07954 3-isobutyl-1-methyl-7H-xanthineDrugbanksmall molecule