Entity Details

Primary name FST_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP19883
EntryNameFST_HUMAN
FullNameFollistatin
TaxID9606
Evidenceevidence at protein level
Length344
SequenceStatuscomplete
DateCreated1991-02-01
DateModified2021-06-02

Ontological Relatives

GenesFST

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0001501 skeletal system development
GO:0002244 hematopoietic progenitor cell differentiation
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0007275 multicellular organism development
GO:0007276 gamete generation
GO:0007389 pattern specification process
GO:0008585 female gonad development
GO:0030154 cell differentiation
GO:0030509 BMP signaling pathway
GO:0030510 regulation of BMP signaling pathway
GO:0031069 hair follicle morphogenesis
GO:0032926 negative regulation of activin receptor signaling pathway
GO:0038102 activin receptor antagonist activity
GO:0042475 odontogenesis of dentin-containing tooth
GO:0043395 heparan sulfate proteoglycan binding
GO:0043616 keratinocyte proliferation
GO:0045596 negative regulation of cell differentiation
GO:0048185 activin binding
GO:0051798 positive regulation of hair follicle development

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR002350 Kazal domainDomainDomain
IPR003645 Follistatin-like, N-terminalDomainDomain
IPR015369 Follistatin/Osteonectin EGF domainDomainDomain
IPR017878 TB domainDomainDomain
IPR036058 Kazal domain superfamilyFamilyHomologous superfamily
IPR036773 TGF-beta binding (TB) domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01666 D-Myo-Inositol-HexasulphateDrugbanksmall molecule