Entity Details

Primary name NTF3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP20783
EntryNameNTF3_HUMAN
FullNameNeurotrophin-3
TaxID9606
Evidenceevidence at protein level
Length257
SequenceStatuscomplete
DateCreated1991-02-01
DateModified2021-06-02

Ontological Relatives

GenesNTF3

GO terms

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GOName
GO:0000187 obsolete activation of MAPK activity
GO:0002092 positive regulation of receptor internalization
GO:0005102 signaling receptor binding
GO:0005163 nerve growth factor receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0007165 signal transduction
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007267 cell-cell signaling
GO:0007399 nervous system development
GO:0007422 peripheral nervous system development
GO:0007613 memory
GO:0008021 synaptic vesicle
GO:0008083 growth factor activity
GO:0008284 positive regulation of cell population proliferation
GO:0010863 positive regulation of phospholipase C activity
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0021675 nerve development
GO:0030335 positive regulation of cell migration
GO:0030424 axon
GO:0030425 dendrite
GO:0032148 activation of protein kinase B activity
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0038180 nerve growth factor signaling pathway
GO:0042056 chemoattractant activity
GO:0042981 regulation of apoptotic process
GO:0043524 negative regulation of neuron apoptotic process
GO:0045664 regulation of neuron differentiation
GO:0048812 neuron projection morphogenesis
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation
GO:0050804 modulation of chemical synaptic transmission
GO:0050930 induction of positive chemotaxis
GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway
GO:0090630 activation of GTPase activity
GO:2000251 positive regulation of actin cytoskeleton reorganization

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR002072 Nerve growth factor-relatedDomainDomain
IPR015578 Neurotrophin-3FamilyFamily
IPR019846 Nerve growth factor conserved siteSiteConserved site
IPR020408 Nerve growth factor-likeFamilyFamily
IPR029034 Cystine-knot cytokineFamilyHomologous superfamily

Diseases

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