Entity Details

Primary name IP3KB_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP27987
EntryNameIP3KB_HUMAN
FullNameInositol-trisphosphate 3-kinase B
TaxID9606
Evidenceevidence at protein level
Length946
SequenceStatuscomplete
DateCreated1992-08-01
DateModified2021-06-02

Ontological Relatives

GenesITPKB

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0000828 inositol hexakisphosphate kinase activity
GO:0001932 regulation of protein phosphorylation
GO:0002262 myeloid cell homeostasis
GO:0005516 calmodulin binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0007165 signal transduction
GO:0007166 cell surface receptor signaling pathway
GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity
GO:0016020 membrane
GO:0016301 kinase activity
GO:0032957 inositol trisphosphate metabolic process
GO:0032958 inositol phosphate biosynthetic process
GO:0033030 negative regulation of neutrophil apoptotic process
GO:0035726 common myeloid progenitor cell proliferation
GO:0043647 inositol phosphate metabolic process
GO:0045059 positive thymic T cell selection
GO:0045638 negative regulation of myeloid cell differentiation
GO:0046579 positive regulation of Ras protein signal transduction
GO:0046638 positive regulation of alpha-beta T cell differentiation
GO:0046854 phosphatidylinositol phosphate biosynthetic process
GO:0071277 cellular response to calcium ion

Subcellular Location

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Domains

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DomainNameCategoryType
IPR005522 Inositol polyphosphate kinaseFamilyFamily
IPR038286 Inositol polyphosphate kinase superfamilyFamilyHomologous superfamily

Diseases

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