Entity Details

Primary name ACADL_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP28330
EntryNameACADL_HUMAN
FullNameLong-chain specific acyl-CoA dehydrogenase, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length430
SequenceStatuscomplete
DateCreated1992-12-01
DateModified2021-04-07

Ontological Relatives

GenesACADL

GO terms

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GOName
GO:0000062 fatty-acyl-CoA binding
GO:0001659 temperature homeostasis
GO:0003995 acyl-CoA dehydrogenase activity
GO:0004466 long-chain-acyl-CoA dehydrogenase activity
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0006635 fatty acid beta-oxidation
GO:0016401 palmitoyl-CoA oxidase activity
GO:0019254 carnitine metabolic process, CoA-linked
GO:0031966 mitochondrial membrane
GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase
GO:0042413 carnitine catabolic process
GO:0042758 long-chain fatty acid catabolic process
GO:0042802 identical protein binding
GO:0044242 cellular lipid catabolic process
GO:0045717 negative regulation of fatty acid biosynthetic process
GO:0046322 negative regulation of fatty acid oxidation
GO:0050660 flavin adenine dinucleotide binding
GO:0090181 regulation of cholesterol metabolic process
GO:0120162 positive regulation of cold-induced thermogenesis

Subcellular Location

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Subcellular Location
Mitochondrion matrix

Domains

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DomainNameCategoryType
IPR006089 Acyl-CoA dehydrogenase, conserved siteSiteConserved site
IPR006091 Acyl-CoA oxidase/dehydrogenase, central domainDomainDomain
IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminalDomainDomain
IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamilyFamilyHomologous superfamily
IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminalDomainDomain
IPR034179 Long-chain specific acyl-CoA dehydrogenaseFamilyFamily
IPR036250 Acyl-CoA dehydrogenase-like, C-terminalFamilyHomologous superfamily
IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
ACADL_HUMANTGM1_HUMANBioGRID, IntAct32296183 details
ACADL_HUMANEXOC1_HUMANIntAct31413325 details