Entity Details

Primary name V2R_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP30518
EntryNameV2R_HUMAN
FullNameVasopressin V2 receptor
TaxID9606
Evidenceevidence at protein level
Length371
SequenceStatuscomplete
DateCreated1993-04-01
DateModified2021-06-02

Ontological Relatives

GenesAVPR2

GO terms

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GOName
GO:0001992 regulation of systemic arterial blood pressure by vasopressin
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0003091 renal water homeostasis
GO:0004930 G protein-coupled receptor activity
GO:0005000 vasopressin receptor activity
GO:0005768 endosome
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
GO:0007190 activation of adenylate cyclase activity
GO:0007588 excretion
GO:0007599 hemostasis
GO:0008285 negative regulation of cell population proliferation
GO:0010628 positive regulation of gene expression
GO:0016021 integral component of membrane
GO:0030139 endocytic vesicle
GO:0030669 clathrin-coated endocytic vesicle membrane
GO:0042277 peptide binding
GO:0045907 positive regulation of vasoconstriction
GO:0048471 perinuclear region of cytoplasm
GO:0061024 membrane organization

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000161 Vasopressin V2 receptorFamilyFamily
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR001817 Vasopressin receptorFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00035 DesmopressinDrugbanksmall molecule
DB00067 VasopressinDrugbanksmall molecule
DB00618 DemeclocyclineDrugbanksmall molecule
DB00872 ConivaptanDrugbanksmall molecule
DB02638 TerlipressinDrugbanksmall molecule
DB05091 M0002Drugbanksmall molecule
DB05838 OPC-51803Drugbanksmall molecule
DB06212 TolvaptanDrugbanksmall molecule
DB09059 AtosibanDrugbanksmall molecule
DB14642 LypressinDrugbanksmall molecule