Entity Details

Primary name 5HT1F_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP30939
EntryName5HT1F_HUMAN
FullName5-hydroxytryptamine receptor 1F
TaxID9606
Evidenceevidence at transcript level
Length366
SequenceStatuscomplete
DateCreated1993-07-01
DateModified2021-06-02

Ontological Relatives

GenesHTR1F

GO terms

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GOName
GO:0004993 G protein-coupled serotonin receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway
GO:0007268 chemical synaptic transmission
GO:0030425 dendrite
GO:0030594 neurotransmitter receptor activity
GO:0045202 synapse
GO:0051378 serotonin binding

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000450 5-Hydroxytryptamine 1F receptorFamilyFamily
IPR002231 5-hydroxytryptamine receptor familyFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00216 EletriptanDrugbanksmall molecule
DB00247 MethysergideDrugbanksmall molecule
DB00315 ZolmitriptanDrugbanksmall molecule
DB00334 OlanzapineDrugbanksmall molecule
DB00669 SumatriptanDrugbanksmall molecule
DB00696 ErgotamineDrugbanksmall molecule
DB00715 ParoxetineDrugbanksmall molecule
DB00952 NaratriptanDrugbanksmall molecule
DB00953 RizatriptanDrugbanksmall molecule
DB01049 Ergoloid mesylateDrugbanksmall molecule
DB01221 KetamineDrugbanksmall molecule
DB01239 ChlorprothixeneDrugbanksmall molecule
DB06148 MianserinDrugbanksmall molecule
DB09304 SetiptilineDrugbanksmall molecule
DB11273 DihydroergocornineDrugbanksmall molecule
DB11732 LasmiditanDrugbanksmall molecule
DB12141 GilteritinibDrugbanksmall molecule
DB13025 TiaprideDrugbanksmall molecule
DB13345 DihydroergocristineDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
5HT1F_HUMANCAV1_HUMANHPRD15190056 details