Entity Details

Primary name ADH7_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP40394
EntryNameADH7_HUMAN
FullNameAll-trans-retinol dehydrogenase [NAD(+)] ADH7
TaxID9606
Evidenceevidence at protein level
Length386
SequenceStatuscomplete
DateCreated1995-02-01
DateModified2021-06-02

Ontological Relatives

GenesADH7

GO terms

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GOName
GO:0001523 retinoid metabolic process
GO:0004022 alcohol dehydrogenase (NAD+) activity
GO:0004024 alcohol dehydrogenase activity, zinc-dependent
GO:0004031 aldehyde oxidase activity
GO:0004745 NAD-retinol dehydrogenase activity
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006068 ethanol catabolic process
GO:0006069 ethanol oxidation
GO:0008270 zinc ion binding
GO:0009617 response to bacterium
GO:0010430 fatty acid omega-oxidation
GO:0019841 retinol binding
GO:0035276 ethanol binding
GO:0042572 retinol metabolic process
GO:0042573 retinoic acid metabolic process
GO:0045471 response to ethanol
GO:0048019 receptor antagonist activity
GO:0050153 omega-hydroxydecanoate dehydrogenase activity

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR002328 Alcohol dehydrogenase, zinc-type, conserved siteSiteConserved site
IPR011032 GroES-like superfamilyFamilyHomologous superfamily
IPR013149 Alcohol dehydrogenase, C-terminalDomainDomain
IPR013154 Alcohol dehydrogenase, N-terminalDomainDomain
IPR028635 Alcohol dehydrogenase family, zinc-type, class-IV subfamilyFamilyFamily
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00157 NADHDrugbanksmall molecule
DB00898 EthanolDrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
ADH7_HUMANUBC_HUMANBioGRID23314748 details
ADH7_HUMANADH7_HUMANBioGRID, HPRD10631979 9228021 details