Entity Details

Primary name OX2G_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP41217
EntryNameOX2G_HUMAN
FullNameOX-2 membrane glycoprotein
TaxID9606
Evidenceevidence at protein level
Length278
SequenceStatuscomplete
DateCreated1995-02-01
DateModified2021-06-02

Ontological Relatives

GenesCD200

GO terms

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GOName
GO:0002695 negative regulation of leukocyte activation
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0008285 negative regulation of cell population proliferation
GO:0009986 cell surface
GO:0016020 membrane
GO:0030424 axon
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0032715 negative regulation of interleukin-6 production
GO:0032793 positive regulation of CREB transcription factor activity
GO:0034113 heterotypic cell-cell adhesion
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043031 negative regulation of macrophage activation
GO:0044297 cell body
GO:0050776 regulation of immune response
GO:0071636 positive regulation of transforming growth factor beta production
GO:0086080 protein binding involved in heterotypic cell-cell adhesion
GO:0098609 cell-cell adhesion
GO:0140081 glycosylated region protein binding
GO:0150072 positive regulation of arginase activity
GO:0150074 positive regulation of protein-glutamine gamma-glutamyltransferase activity
GO:0150077 regulation of neuroinflammatory response
GO:0150079 negative regulation of neuroinflammatory response
GO:1901215 negative regulation of neuron death
GO:1904465 negative regulation of matrix metallopeptidase secretion
GO:1905522 negative regulation of macrophage migration
GO:2000405 negative regulation of T cell migration

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013106 Immunoglobulin V-set domainDomainDomain
IPR013151 ImmunoglobulinDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR033321 OX-2 membrane glycoproteinFamilyFamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
OX2G_HUMANHUS1_HUMANBioGRID, IntAct21988832 details
OX2G_HUMANMO2R1_HUMANBioGRID, HPRD, IntAct10981966 12960329 21982860 details
OX2G_HUMANOX2R_HUMANHPRD10981966 details