Entity Details

Primary name XCL1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP47992
EntryNameXCL1_HUMAN
FullNameLymphotactin
TaxID9606
Evidenceevidence at protein level
Length114
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesXCL1

GO terms

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GOName
GO:0001916 positive regulation of T cell mediated cytotoxicity
GO:0002548 monocyte chemotaxis
GO:0002690 positive regulation of leukocyte chemotaxis
GO:0002725 negative regulation of T cell cytokine production
GO:0002726 positive regulation of T cell cytokine production
GO:0002826 negative regulation of T-helper 1 type immune response
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006954 inflammatory response
GO:0007165 signal transduction
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007267 cell-cell signaling
GO:0008009 chemokine activity
GO:0009615 response to virus
GO:0010820 positive regulation of T cell chemotaxis
GO:0030593 neutrophil chemotaxis
GO:0031640 killing of cells of other organism
GO:0032689 negative regulation of interferon-gamma production
GO:0032703 negative regulation of interleukin-2 production
GO:0032733 positive regulation of interleukin-10 production
GO:0035782 mature natural killer cell chemotaxis
GO:0042379 chemokine receptor binding
GO:0042803 protein homodimerization activity
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0043547 positive regulation of GTPase activity
GO:0045892 negative regulation of transcription, DNA-templated
GO:0048020 CCR chemokine receptor binding
GO:0048247 lymphocyte chemotaxis
GO:0050727 regulation of inflammatory response
GO:0051209 release of sequestered calcium ion into cytosol
GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide
GO:0070098 chemokine-mediated signaling pathway
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071346 cellular response to interferon-gamma
GO:0071347 cellular response to interleukin-1
GO:0071353 cellular response to interleukin-4
GO:0071356 cellular response to tumor necrosis factor
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:0071636 positive regulation of transforming growth factor beta production
GO:0071663 positive regulation of granzyme B production
GO:0090023 positive regulation of neutrophil chemotaxis
GO:2000412 positive regulation of thymocyte migration
GO:2000503 positive regulation of natural killer cell chemotaxis
GO:2000513 positive regulation of granzyme A production
GO:2000518 negative regulation of T-helper 1 cell activation
GO:2000538 positive regulation of B cell chemotaxis
GO:2000553 positive regulation of T-helper 2 cell cytokine production
GO:2000556 positive regulation of T-helper 1 cell cytokine production
GO:2000558 positive regulation of immunoglobulin production in mucosal tissue
GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation
GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation
GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR001811 Chemokine interleukin-8-like domainDomainDomain
IPR008105 C chemokineFamilyFamily
IPR036048 Chemokine interleukin-8-like superfamilyFamilyHomologous superfamily
IPR039809 Chemokine beta/gamma/deltaFamilyFamily

Diseases

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