Entity Details

Primary name AGRE5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP48960
EntryNameAGRE5_HUMAN
FullNameAdhesion G protein-coupled receptor E5
TaxID9606
Evidenceevidence at protein level
Length835
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesADGRE5

GO terms

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GOName
GO:0004888 transmembrane signaling receptor activity
GO:0004930 G protein-coupled receptor activity
GO:0005509 calcium ion binding
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005925 focal adhesion
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0007155 cell adhesion
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007267 cell-cell signaling
GO:0016020 membrane
GO:0030667 secretory granule membrane
GO:0043312 neutrophil degranulation
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cell membrane
Secreted

Domains

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DomainNameCategoryType
IPR000152 EGF-type aspartate/asparagine hydroxylation sitePTMPTM
IPR000203 GPS motifDomainDomain
IPR000742 EGF-like domainDomainDomain
IPR000832 GPCR, family 2, secretin-likeFamilyFamily
IPR001881 EGF-like calcium-binding domainDomainDomain
IPR003056 GPCR, family 2, ADGRE2/ADGRE5FamilyFamily
IPR009030 Growth factor receptor cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR017981 GPCR, family 2-likeDomainDomain
IPR017983 GPCR, family 2, secretin-like, conserved siteSiteConserved site
IPR018097 EGF-like calcium-binding, conserved siteSiteConserved site

Diseases

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