Entity Details

Primary name LUM_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP51884
EntryNameLUM_HUMAN
FullNameLumican
TaxID9606
Evidenceevidence at protein level
Length338
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesLUM

GO terms

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GOName
GO:0005201 extracellular matrix structural constituent
GO:0005518 collagen binding
GO:0005576 extracellular region
GO:0005583 fibrillar collagen trimer
GO:0005615 extracellular space
GO:0005796 Golgi lumen
GO:0007601 visual perception
GO:0014070 response to organic cyclic compound
GO:0018146 keratan sulfate biosynthetic process
GO:0030021 extracellular matrix structural constituent conferring compression resistance
GO:0030198 extracellular matrix organization
GO:0030199 collagen fibril organization
GO:0031012 extracellular matrix
GO:0032914 positive regulation of transforming growth factor beta1 production
GO:0042340 keratan sulfate catabolic process
GO:0043202 lysosomal lumen
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0051216 cartilage development
GO:0062023 collagen-containing extracellular matrix
GO:0070062 extracellular exosome
GO:0070848 response to growth factor

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000372 Leucine-rich repeat N-terminal domainDomainDomain
IPR001611 Leucine-rich repeatRepeatRepeat
IPR003591 Leucine-rich repeat, typical subtypeRepeatRepeat
IPR027219 LumicanFamilyFamily
IPR032675 Leucine-rich repeat domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB09130 CopperDrugbanksmall molecule