Entity Details

Primary name THOP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP52888
EntryNameTHOP1_HUMAN
FullNameThimet oligopeptidase
TaxID9606
Evidenceevidence at protein level
Length689
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesTHOP1

GO terms

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GOName
GO:0000209 protein polyubiquitination
GO:0004222 metalloendopeptidase activity
GO:0005758 mitochondrial intermembrane space
GO:0005829 cytosol
GO:0006508 proteolysis
GO:0006518 peptide metabolic process
GO:0042277 peptide binding
GO:0046872 metal ion binding

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR001567 Peptidase M3A/M3B catalytic domainDomainDomain
IPR024077 Neurolysin/Thimet oligopeptidase, domain 2FamilyHomologous superfamily
IPR024079 Metallopeptidase, catalytic domain superfamilyFamilyHomologous superfamily
IPR024080 Neurolysin/Thimet oligopeptidase, N-terminalFamilyHomologous superfamily

Diseases

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