Entity Details

Primary name NUP98_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP52948
EntryNameNUP98_HUMAN
FullNameNuclear pore complex protein Nup98-Nup96
TaxID9606
Evidenceevidence at protein level
Length1817
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesNUP98

GO terms

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GOName
GO:0003713 transcription coactivator activity
GO:0003729 mRNA binding
GO:0005215 transporter activity
GO:0005635 nuclear envelope
GO:0005643 nuclear pore
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006110 regulation of glycolytic process
GO:0006406 mRNA export from nucleus
GO:0006409 tRNA export from nucleus
GO:0006606 protein import into nucleus
GO:0006913 nucleocytoplasmic transport
GO:0006999 nuclear pore organization
GO:0007052 mitotic spindle organization
GO:0007084 mitotic nuclear membrane reassembly
GO:0008139 nuclear localization sequence binding
GO:0008236 serine-type peptidase activity
GO:0016032 viral process
GO:0016604 nuclear body
GO:0016925 protein sumoylation
GO:0017056 structural constituent of nuclear pore
GO:0019058 viral life cycle
GO:0019083 viral transcription
GO:0031080 nuclear pore outer ring
GO:0031965 nuclear membrane
GO:0034399 nuclear periphery
GO:0042405 nuclear inclusion body
GO:0043231 intracellular membrane-bounded organelle
GO:0043657 host cell
GO:0044615 nuclear pore nuclear basket
GO:0048026 positive regulation of mRNA splicing, via spliceosome
GO:0051292 nuclear pore complex assembly
GO:0060964 regulation of gene silencing by miRNA
GO:0075733 intracellular transport of virus
GO:1900034 regulation of cellular response to heat
GO:1990841 promoter-specific chromatin binding
GO:1990904 ribonucleoprotein complex

Subcellular Location

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Subcellular Location
Nucleus
Nucleus membrane

Domains

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DomainNameCategoryType
IPR007230 Peptidase S59, nucleoporinDomainDomain
IPR021967 Nuclear protein 96DomainDomain
IPR036903 Peptidase S59, nucleoporin superfamilyFamilyHomologous superfamily
IPR037637 Nuclear pore complex protein NUP98-NUP96FamilyFamily
IPR037665 Nucleoporin peptidase S59-likeFamilyFamily

Diseases

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Interactions

35 interactions

InteractorPartnerSourcesPublicationsLink
NUP98_HUMANNXF1_HUMANBioGRID, HPRD, MINT, UniProt10668806 11073998 11551912 16314397 22334672 29395067 details
NUP98_HUMANAPC_HUMANBioGRID, IntAct20936779 details
NUP98_HUMANCSK21_HUMANBioGRID, IntAct22113938 details
NUP98_HUMANIMB1_HUMANBioGRID, HPRD, IntAct25562883 26344197 26496610 33097660 9144189 9275187 details
NUP98_HUMANNUP88_HUMANBioGRID, HPRD, IntAct12589057 22480613 28514442 details
NUP98_HUMANSEC13_HUMANBioGRID, HPRD, IntAct14517296 24981860 26186194 28514442 details
NUP98_HUMANRAE1L_HUMANBioGRID, DIP, HPRD, IntAct10209021 15851029 17172455 18832153 19615732 20498086 21467841 24927547 26186194 26344197 27097363 28514442 33097660 details
NUP98_HUMANPCNA_HUMANUniProt26030842 details
NUP98_HUMANTPR_HUMANBioGRID, HPRD11248057 12802065 details
NUP98_HUMANCBP_HUMANBioGRID, HPRD16651408 9858599 details
NUP98_HUMANTNPO2_HUMANBioGRID10875935 details
NUP98_HUMANTNPO1_HUMANBioGRID, HPRD10875935 26344197 9144189 details
NUP98_HUMANHDAC1_HUMANBioGRID16651408 details
NUP98_HUMANNU155_HUMANBioGRID29899397 34079125 details
NUP98_HUMANDYLT1_HUMANBioGRID23840580 details
NUP98_HUMANNFX1_HUMANBioGRID31375530 details
NUP98_HUMANNU107_HUMANBioGRID, IntAct11564755 17360435 20676042 24927568 24981860 26344197 26496610 details
NUP98_HUMANHNRL1_HUMANBioGRID, MINT19745842 details
NUP98_HUMANTNIK_HUMANIntAct31413325 details
NUP98_HUMANNUP98_HUMANDIP, HPRD12589057 29439243 9114010 details
NUP98_HUMANEP300_HUMANBioGRID, HPRD9858599 details
NUP98_HUMANNPM_HUMANBioGRID14968112 details
NUP98_HUMANPTTG1_HUMANBioGRID16479161 details
NUP98_HUMANRPGF3_HUMANBioGRID20547757 details
NUP98_HUMANNUMA1_HUMANBioGRID17172455 details
NUP98_HUMANCDC27_HUMANBioGRID27097363 details
NUP98_HUMANAPC4_HUMANBioGRID27097363 details
NUP98_HUMANAPC10_HUMANBioGRID27097363 details
NUP98_HUMANMD2L1_HUMANBioGRID27097363 details
NUP98_HUMANCDC20_HUMANBioGRID27097363 details
NUP98_HUMANFZR1_HUMANBioGRID27097363 details
NUP98_HUMANPIN1_HUMANBioGRID27097363 details
NUP98_HUMANRCC1_HUMANHPRD10875935 details
NUP98_HUMANIPO5_HUMANHPRD9114010 details
NUP98_HUMANNUP62_HUMANHPRD8707840 details