Entity Details

Primary name ACTHR_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ01718
EntryNameACTHR_HUMAN
FullNameAdrenocorticotropic hormone receptor
TaxID9606
Evidenceevidence at protein level
Length297
SequenceStatuscomplete
DateCreated1993-07-01
DateModified2021-06-02

Ontological Relatives

GenesMC2R

GO terms

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GOName
GO:0001890 placenta development
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0004930 G protein-coupled receptor activity
GO:0004977 melanocortin receptor activity
GO:0004978 corticotropin receptor activity
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0019222 regulation of metabolic process

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR001168 Adrenocorticotrophin (ACTH) receptorFamilyFamily
IPR001671 Melanocortin/ACTH receptorFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB01284 TetracosactideDrugbanksmall molecule
DB01285 CorticotropinDrugbankbiotech
DB09334 Seractide acetateDrugbankbiotech
DB11653 BremelanotideDrugbanksmall molecule