Entity Details

Primary name ROR1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ01973
EntryNameROR1_HUMAN
FullNameInactive tyrosine-protein kinase transmembrane receptor ROR1
TaxID9606
Evidenceevidence at protein level
Length937
SequenceStatuscomplete
DateCreated2001-04-27
DateModified2021-06-02

Ontological Relatives

GenesROR1

GO terms

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GOName
GO:0001725 stress fiber
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007275 multicellular organism development
GO:0007605 sensory perception of sound
GO:0009986 cell surface
GO:0010976 positive regulation of neuron projection development
GO:0014002 astrocyte development
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0017147 Wnt-protein binding
GO:0033674 positive regulation of kinase activity
GO:0042813 Wnt-activated receptor activity
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043235 receptor complex
GO:0043410 positive regulation of MAPK cascade
GO:0043679 axon terminus
GO:0048839 inner ear development
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway

Subcellular Location

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Subcellular Location
Cell projection
Membrane

Domains

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DomainNameCategoryType
IPR000001 KringleDomainDomain
IPR000719 Protein kinase domainDomainDomain
IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domainDomainDomain
IPR003598 Immunoglobulin subtype 2DomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR008266 Tyrosine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR013098 Immunoglobulin I-setDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR013806 Kringle-like foldFamilyHomologous superfamily
IPR016247 Tyrosine-protein kinase, receptor RORFamilyFamily
IPR018056 Kringle, conserved siteSiteConserved site
IPR020067 Frizzled domainDomainDomain
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily
IPR036790 Frizzled cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR038178 Kringle superfamilyFamilyHomologous superfamily

Diseases

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