Entity Details

Primary name CDH5
Entity type gene
Source Source Link

Details

PrimaryID1003
RefseqGene
SymbolCDH5
Namecadherin 5
Chromosome16
Location16q21
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-12-14
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsCADH5_HUMAN

GO terms

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GOName
GO:0000902 cell morphogenesis
GO:0001932 regulation of protein phosphorylation
GO:0001944 vasculature development
GO:0001955 blood vessel maturation
GO:0005102 signaling receptor binding
GO:0005509 calcium ion binding
GO:0005654 nucleoplasm
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0005912 adherens junction
GO:0005923 bicellular tight junction
GO:0006874 cellular calcium ion homeostasis
GO:0007043 cell-cell junction assembly
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0007275 multicellular organism development
GO:0008013 beta-catenin binding
GO:0008285 negative regulation of cell population proliferation
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0010628 positive regulation of gene expression
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0016342 catenin complex
GO:0019903 protein phosphatase binding
GO:0030054 cell junction
GO:0030335 positive regulation of cell migration
GO:0030513 positive regulation of BMP signaling pathway
GO:0031115 negative regulation of microtubule polymerization
GO:0031334 positive regulation of protein-containing complex assembly
GO:0031965 nuclear membrane
GO:0034332 adherens junction organization
GO:0035307 positive regulation of protein dephosphorylation
GO:0035633 maintenance of blood-brain barrier
GO:0043114 regulation of vascular permeability
GO:0043184 vascular endothelial growth factor receptor 2 binding
GO:0043534 blood vessel endothelial cell migration
GO:0044325 transmembrane transporter binding
GO:0044331 cell-cell adhesion mediated by cadherin
GO:0045296 cadherin binding
GO:0045766 positive regulation of angiogenesis
GO:0050728 negative regulation of inflammatory response
GO:0070051 fibrinogen binding
GO:0070700 BMP receptor binding
GO:0070830 bicellular tight junction assembly
GO:0098609 cell-cell adhesion
GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules
GO:1902396 protein localization to bicellular tight junction
GO:1903142 positive regulation of establishment of endothelial barrier
GO:1990782 protein tyrosine kinase binding
GO:2000114 regulation of establishment of cell polarity
GO:2000352 negative regulation of endothelial cell apoptotic process

Diseases

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Interactions

97 interactions

InteractorPartnerSourcesPublicationsLink
CDH5SHC1BioGRID, HPRD, MINT11950700 details
CDH5CTNNB1bhf-ucl, BioGRID, HPRD, IntAct, MINT, Molecular Connections12003790 12413882 17057644 18287330 18662404 20123964 20224040 22519731 22720799 23243000 28514442 9434630 details
CDH5PKP4BioGRID, HPRD, IntAct12426320 28514442 details
CDH5WARS1DIP20010843 details
CDH5HTRA4IntAct30638949 details
CDH5JUPBioGRID, HPRD12003790 9434630 9739078 details
CDH5PTPRBBioGRID, HPRD12234928 details
CDH5DSPBioGRID, HPRD9739078 details
CDH5FGABioGRID, HPRD11900554 details
CDH5EGFRBioGRID24658140 25402006 details
CDH5KDRBioGRID, HPRD, MINT, Molecular Connections10428027 11950700 18662404 25657827 details
CDH5PARD3MINT17057644 details
CDH5CTNNA1BioGRID, HPRD, IntAct, MINT12003790 17057644 28514442 9434630 details
CDH5PARD6AHPRD, MINT17057644 details
CDH5PARD6GMINT17057644 details
CDH5SRCHPRD, MINT16027153 16909109 details
CDH5CTNNBIP1bhf-ucl18287330 details
CDH5CTNND1BioGRID, HPRD, IntAct11855855 28514442 9378757 details
CDH5P2RX4BioGRID, HPRD12088286 details
CDH5PTPN11BioGRID, HPRD10681592 details
CDH5VIMBioGRID, HPRD12003790 details
CDH5PTK2BioGRID22720799 details
CDH5BMPR2BioGRID26598555 details
CDH5P2RY2BioGRID25657827 details
CDH5VCLBioGRID26923917 details
CDH5PRKCABioGRID22519731 details
CDH5SMG1HPRD10428027 details
CDH5P2RX6HPRD12088286 details
CDH5EPHA2HPRD16481735 details
CDH5CSKHPRD15861137 details
CDH5F2RL2HPRD17057644 details
CDH5TJP1Molecular Connections18662404 details
CDH5GPAMBioGRID, IntAct28514442 details
CDH5ITFG1BioGRID, IntAct28514442 details
CDH5TSSC4BioGRID, IntAct28514442 details
CDH5TBL2BioGRID, IntAct28514442 details
CDH5MYO5ABioGRID, IntAct28514442 details
CDH5EXOGBioGRID, IntAct28514442 details
CDH5SCML1BioGRID, IntAct28514442 details
CDH5VANGL2BioGRID, IntAct28514442 details
CDH5KIDINS220BioGRID, IntAct28514442 details
CDH5ZNHIT2BioGRID, IntAct28514442 details
CDH5VTI1BBioGRID, IntAct28514442 details
CDH5LRFN1BioGRID, IntAct28514442 details
CDH5TMEM39ABioGRID, IntAct28514442 details
CDH5ST7BioGRID, IntAct28514442 details
CDH5MYO5CBioGRID, IntAct28514442 details
CDH5MICU1BioGRID, IntAct28514442 details
CDH5DNAJC1BioGRID, IntAct28514442 details
CDH5POM121BioGRID, IntAct28514442 details
CDH5MCRS1BioGRID, IntAct28514442 details
CDH5SARAFBioGRID, IntAct28514442 details
CDH5PTPRUBioGRID, IntAct28514442 details
CDH5UTP15BioGRID, IntAct28514442 details
CDH5PDZD8BioGRID, IntAct28514442 details
CDH5MACO1BioGRID, IntAct28514442 details
CDH5RBFABioGRID, IntAct28514442 details
CDH5ASPMBioGRID, IntAct28514442 details
CDH5MICU2BioGRID, IntAct28514442 details
CDH5PNPLA6BioGRID, IntAct28514442 details
CDH5WDR75BioGRID, IntAct28514442 details
CDH5CEP57BioGRID, IntAct28514442 details
CDH5ACAD11BioGRID, IntAct28514442 details
CDH5TMTC3BioGRID, IntAct28514442 details
CDH5PKN3BioGRID, IntAct28514442 details
CDH5ZMYM1BioGRID, IntAct28514442 details
CDH5TIGD5BioGRID, IntAct28514442 details
CDH5KCNJ8BioGRID, IntAct28514442 details
CDH5IQCB1BioGRID, IntAct28514442 details
CDH5LTBP1BioGRID, IntAct28514442 details
CDH5KCNJ11BioGRID, IntAct28514442 details
CDH5KEAP1BioGRID, IntAct28514442 details
CDH5DAG1BioGRID, IntAct28514442 details
CDH5MYO9BBioGRID, IntAct28514442 details
CDH5PLD1BioGRID, IntAct28514442 details
CDH5SREBF2BioGRID, IntAct28514442 details
CDH5RRP1BioGRID, IntAct28514442 details
CDH5HADHBBioGRID, IntAct28514442 details
CDH5PIK3CBBioGRID, IntAct28514442 details
CDH5TNFSF9BioGRID, IntAct28514442 details
CDH5HADHABioGRID, IntAct28514442 details
CDH5RYKBioGRID, IntAct28514442 details
CDH5CTNNA2BioGRID, IntAct28514442 details
CDH5OSBPBioGRID, IntAct28514442 details
CDH5ATF6BioGRID, IntAct28514442 details
CDH5POP4BioGRID, IntAct28514442 details
CDH5POLR1ABioGRID, IntAct28514442 details
CDH5SGPL1BioGRID, IntAct28514442 details
CDH5SBF1BioGRID, IntAct28514442 details
CDH5MYO1DBioGRID, IntAct28514442 details
CDH5CAPN15BioGRID, IntAct28514442 details
CDH5SNRNP200BioGRID, IntAct28514442 details
CDH5MYO1BBioGRID, IntAct28514442 details
CDH5PLD2BioGRID, IntAct28514442 details
CDH5POLR3ABioGRID, IntAct28514442 details
CDH5ARVCFBioGRID, IntAct28514442 details
CDH5MYCNIntAct27728805 details