Entity Details

Primary name RASGRP1
Entity type gene
Source Source Link

Details

PrimaryID10125
RefseqGeneNG_023268
SymbolRASGRP1
NameRAS guanyl releasing protein 1
Chromosome15
Location15q14
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-06-02
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsGRP1_HUMAN

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0000165 MAPK cascade
GO:0001934 positive regulation of protein phosphorylation
GO:0002250 adaptive immune response
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005509 calcium ion binding
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007165 signal transduction
GO:0007265 Ras protein signal transduction
GO:0008270 zinc ion binding
GO:0008289 lipid binding
GO:0016020 membrane
GO:0019992 diacylglycerol binding
GO:0030101 natural killer cell activation
GO:0030154 cell differentiation
GO:0031210 phosphatidylcholine binding
GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production
GO:0032729 positive regulation of interferon-gamma production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0042098 T cell proliferation
GO:0042100 B cell proliferation
GO:0042110 T cell activation
GO:0042113 B cell activation
GO:0042802 identical protein binding
GO:0043406 positive regulation of MAP kinase activity
GO:0043547 positive regulation of GTPase activity
GO:0045954 positive regulation of natural killer cell mediated cytotoxicity
GO:0046330 positive regulation of JNK cascade
GO:0046579 positive regulation of Ras protein signal transduction
GO:0070372 regulation of ERK1 and ERK2 cascade
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0090630 activation of GTPase activity

Diseases

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Interactions

7 interactions

InteractorPartnerSourcesPublicationsLink
RASGRP1FMR1IntAct31413325 details
RASGRP1DGKZBioGRID, HPRD11257115 details
RASGRP1HRASHPRD9582122 details
RASGRP1VHLBioGRID, IntAct17353931 details
RASGRP1PPM1BBioGRID, IntAct17353931 details
RASGRP1ABCB8BioGRID22939629 details
RASGRP1APEX1BioGRID28986522 details