Entity Details

Primary name HYAL1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ12794
EntryNameHYAL1_HUMAN
FullNameHyaluronidase-1
TaxID9606
Evidenceevidence at protein level
Length435
SequenceStatuscomplete
DateCreated2005-10-25
DateModified2021-06-02

Ontological Relatives

GenesHYAL1

GO terms

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GOName
GO:0000302 response to reactive oxygen species
GO:0004415 hyalurononglucosaminidase activity
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005975 carbohydrate metabolic process
GO:0006954 inflammatory response
GO:0008134 transcription factor binding
GO:0009615 response to virus
GO:0010634 positive regulation of epithelial cell migration
GO:0030207 chondroitin sulfate catabolic process
GO:0030212 hyaluronan metabolic process
GO:0030213 hyaluronan biosynthetic process
GO:0030214 hyaluronan catabolic process
GO:0030307 positive regulation of cell growth
GO:0030308 negative regulation of cell growth
GO:0031410 cytoplasmic vesicle
GO:0036117 hyaluranon cable
GO:0036120 cellular response to platelet-derived growth factor stimulus
GO:0043202 lysosomal lumen
GO:0044344 cellular response to fibroblast growth factor stimulus
GO:0045766 positive regulation of angiogenesis
GO:0045785 positive regulation of cell adhesion
GO:0045927 positive regulation of growth
GO:0046677 response to antibiotic
GO:0046718 viral entry into host cell
GO:0050501 hyaluronan synthase activity
GO:0050679 positive regulation of epithelial cell proliferation
GO:0051216 cartilage development
GO:0060272 embryonic skeletal joint morphogenesis
GO:0070062 extracellular exosome
GO:0071347 cellular response to interleukin-1
GO:0071356 cellular response to tumor necrosis factor
GO:0071467 cellular response to pH
GO:0071493 cellular response to UV-B
GO:1900087 positive regulation of G1/S transition of mitotic cell cycle
GO:1900106 positive regulation of hyaluranon cable assembly

Subcellular Location

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Subcellular Location
Lysosome
Secreted

Domains

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DomainNameCategoryType
IPR013785 Aldolase-type TIM barrelFamilyHomologous superfamily
IPR017853 Glycoside hydrolase superfamilyFamilyHomologous superfamily
IPR018155 HyaluronidaseFamilyFamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
HYAL1_HUMANCO2A1_HUMANBioGRID, IntAct21988832 details