Entity Details

Primary name SORBS1
Entity type gene
Source Source Link

Details

PrimaryID10580
RefseqGeneNG_034041
SymbolSORBS1
Namesorbin and SH3 domain containing 1
Chromosome10
Location10q24.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-03-20
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSRBS1_HUMAN

GO terms

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GOName
GO:0001725 stress fiber
GO:0003779 actin binding
GO:0005158 insulin receptor binding
GO:0005634 nucleus
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005912 adherens junction
GO:0005915 zonula adherens
GO:0005925 focal adhesion
GO:0006936 muscle contraction
GO:0007160 cell-matrix adhesion
GO:0008092 cytoskeletal protein binding
GO:0008286 insulin receptor signaling pathway
GO:0016363 nuclear matrix
GO:0030055 cell-substrate junction
GO:0030159 signaling receptor complex adaptor activity
GO:0032869 cellular response to insulin stimulus
GO:0043149 stress fiber assembly
GO:0045121 membrane raft
GO:0045725 positive regulation of glycogen biosynthetic process
GO:0046326 positive regulation of glucose import
GO:0046628 positive regulation of insulin receptor signaling pathway
GO:0046889 positive regulation of lipid biosynthetic process
GO:0048041 focal adhesion assembly
GO:1903078 positive regulation of protein localization to plasma membrane

Diseases

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Interactions

75 interactions

InteractorPartnerSourcesPublicationsLink
SORBS1SEMA6ABioGRID, HPRD, IntAct12421765 details
SORBS1ABL1BioGRID, HPRD, IntAct11374898 19891780 details
SORBS1PAK2HPRD, MINT16374509 details
SORBS1ADAM15HPRD, MINT16374509 details
SORBS1INPPL1BioGRID, HPRD, IntAct12504111 details
SORBS1MAP4K3BioGRID, IntAct20936779 details
SORBS1RPL4BioGRID, IntAct21988832 details
SORBS1SLC10A3BioGRID, IntAct21988832 details
SORBS1PILRABioGRID, IntAct21988832 details
SORBS1CDK6BioGRID, IntAct22094256 details
SORBS1ABI1BioGRID, IntAct23414517 details
SORBS1ATXN7MINT23892081 details
SORBS1HTTIntAct17500595 details
SORBS1RTN4IP1BioGRID, IntAct32296183 details
SORBS1KHDRBS1BioGRID, IntAct22745667 31413325 details
SORBS1INSM1BioGRID, HPRD12079283 details
SORBS1CBLBioGRID, HPRD11001060 12504111 15128873 17548467 details
SORBS1FLOT1BioGRID, HPRD11001060 11481476 15128873 15939299 17548467 details
SORBS1AFDNBioGRID10085297 34079125 details
SORBS1VCLBioGRID, HPRD10085297 12765336 17082770 34079125 details
SORBS1SRCBioGRID19891780 details
SORBS1FRS2BioGRID22235335 details
SORBS1TENM1BioGRID15777793 details
SORBS1PGRHPRD12650714 details
SORBS1INSRBioGRID, HPRD, IntAct11374898 details
SORBS1DNM2MINT19116150 details
SORBS1MYCIntAct20195357 details
SORBS1SMAD2IntAct20195357 details
SORBS1CASS4IntAct31413325 details
SORBS1CASP8BioGRID12765336 details
SORBS1NTRK1BioGRID17548467 details
SORBS1SH2B2BioGRID, HPRD11997497 15031295 17548467 details
SORBS1SOS1BioGRID17548467 details
SORBS1EFNB1BioGRID, HPRD11557983 details
SORBS1NCK2BioGRID11557983 details
SORBS1LZTS2BioGRID29395067 details
SORBS1GARRE1BioGRID29395067 details
SORBS1PXNBioGRID, HPRD17082770 34079125 details
SORBS1ACTA1HPRD17082770 details
SORBS1EIF6BioGRID, IntAct17353931 details
SORBS1ACTBBioGRID, MINT19116150 34079125 details
SORBS1YWHABBioGRID, IntAct24255178 details
SORBS1CDK4BioGRID, IntAct26496610 details
SORBS1TGS1BioGRID, IntAct26496610 details
SORBS1CEP128BioGRID, IntAct26638075 details
SORBS1CNTRLBioGRID, IntAct26638075 details
SORBS1FBF1BioGRID, IntAct26638075 details
SORBS1PLEKHA7IntAct28877994 details
SORBS1YWHAGIntAct28514442 details
SORBS1YWHAHIntAct28514442 details
SORBS1EZRBioGRID, IntAct29568061 34079125 details
SORBS1PRNPBioGRID, UniProt29791485 details
SORBS1RIN3BioGRID, IntAct32552912 details
SORBS1LATS2BioGRID24255178 details
SORBS1CDH1BioGRID25468996 details
SORBS1G3BP1BioGRID26777405 details
SORBS1ACTC1BioGRID30890647 details
SORBS1DCAF15BioGRID31452512 details
SORBS1DYNC1LI1BioGRID28718761 details
SORBS1DYNC1LI2BioGRID28718761 details
SORBS1BICD1BioGRID28718761 details
SORBS1BICD2BioGRID28718761 details
SORBS1KIF14BioGRID31586073 details
SORBS1ACTR3BioGRID34079125 details
SORBS1CTNNA1BioGRID34079125 details
SORBS1CTNNB1BioGRID34079125 details
SORBS1CXADRBioGRID34079125 details
SORBS1PARD3BioGRID34079125 details
SORBS1PRPHBioGRID34079125 details
SORBS1SYNE3BioGRID34079125 details
SORBS1TJP2BioGRID34079125 details
SORBS1VASPBioGRID34079125 details
SORBS1VIMBioGRID34079125 details
SORBS1ZYXBioGRID34079125 details
SORBS1VIRMABioGRID29507755 details