Entity Details

Primary name BIRC1_HUMAN
Entity type UniProt
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Details

AccessionQ13075
EntryNameBIRC1_HUMAN
FullNameBaculoviral IAP repeat-containing protein 1
TaxID9606
Evidenceevidence at protein level
Length1403
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesNAIP

GO terms

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GOName
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0006954 inflammatory response
GO:0007399 nervous system development
GO:0016045 detection of bacterium
GO:0016323 basolateral plasma membrane
GO:0042742 defense response to bacterium
GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043524 negative regulation of neuron apoptotic process
GO:0045087 innate immune response
GO:0046872 metal ion binding
GO:0070269 pyroptosis
GO:0072557 IPAF inflammasome complex

Subcellular Location

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Domains

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DomainNameCategoryType
IPR001370 BIR repeatRepeatRepeat
IPR003593 AAA+ ATPase domainDomainDomain
IPR007111 NACHT nucleoside triphosphataseDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR028789 Baculoviral IAP repeat-containing protein 1FamilyFamily
IPR032675 Leucine-rich repeat domain superfamilyFamilyHomologous superfamily
IPR040535 NLRC4, helical domainDomainDomain
IPR041075 NOD2, winged helix domainDomainDomain

Diseases

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