Entity Details

Primary name SPPL3
Entity type gene
Source Source Link

Details

PrimaryID121665
RefseqGene
SymbolSPPL3
Namesignal peptide peptidase like 3
Chromosome12
Location12q24.31
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-11-29
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSPPL3_HUMAN

GO terms

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GOName
GO:0005791 rough endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0006465 signal peptide processing
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0016020 membrane
GO:0030660 Golgi-associated vesicle membrane
GO:0032092 positive regulation of protein binding
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane
GO:0033619 membrane protein proteolysis
GO:0035307 positive regulation of protein dephosphorylation
GO:0042500 aspartic endopeptidase activity, intramembrane cleaving
GO:0042803 protein homodimerization activity
GO:0043231 intracellular membrane-bounded organelle
GO:0050852 T cell receptor signaling pathway
GO:0070886 positive regulation of calcineurin-NFAT signaling cascade
GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane
GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane

Diseases

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Interactions

17 interactions

InteractorPartnerSourcesPublicationsLink
SPPL3PDCD1BioGRID, IntAct28514442 details
SPPL3YIPF3BioGRID, IntAct28514442 details
SPPL3C3AR1BioGRID, IntAct28514442 details
SPPL3ADGRG5BioGRID, IntAct28514442 details
SPPL3SLC15A1BioGRID, IntAct28514442 details
SPPL3SLC2A12BioGRID, IntAct28514442 details
SPPL3SLC18A1BioGRID, IntAct28514442 details
SPPL3SLC1A5BioGRID, IntAct28514442 details
SPPL3SLC6A15BioGRID, IntAct28514442 details
SPPL3TPRA1BioGRID, IntAct28514442 details
SPPL3SPPL2BBioGRID, IntAct28514442 details
SPPL3SLC22A16BioGRID, IntAct28514442 details
SPPL3HTR3ABioGRID, IntAct28514442 details
SPPL3CHRNDBioGRID, IntAct28514442 details
SPPL3P2RX2BioGRID, IntAct28514442 details
SPPL3SLC39A8BioGRID, IntAct28514442 details
SPPL3ELAVL1BioGRID19322201 details