Entity Details

Primary name CRYM
Entity type gene
Source Source Link

Details

PrimaryID1428
RefseqGeneNG_011610
SymbolCRYM
Namecrystallin mu
Chromosome16
Location16p12.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1993-01-14
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsCRYM_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0003714 transcription corepressor activity
GO:0005737 cytoplasm
GO:0005782 peroxisomal matrix
GO:0005829 cytosol
GO:0006554 lysine catabolic process
GO:0007605 sensory perception of sound
GO:0042403 thyroid hormone metabolic process
GO:0042562 hormone binding
GO:0042803 protein homodimerization activity
GO:0047127 thiomorpholine-carboxylate dehydrogenase activity
GO:0050661 NADP binding
GO:0070062 extracellular exosome
GO:0070324 thyroid hormone binding
GO:0070327 thyroid hormone transport

Diseases

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Disease IDSourceNameDescription
616357 OMIMDeafness, autosomal dominant, 40 (DFNA40)A form of non-syndromic sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. The disease is caused by variants affecting the gene represented in this entry.

Interactions

8 interactions

InteractorPartnerSourcesPublicationsLink
CRYMC7orf25BioGRID, MINT21900206 details
CRYMCDC37BioGRID, MINT21900206 details
CRYMTERF1bhf-ucl, BioGRID21044950 details
CRYMADRB2BioGRID, MINT28298427 details
CRYMOPTNIntAct32814053 details
CRYMTGBioGRID9328354 details
CRYMRNF126BioGRID, IntAct26186194 28514442 details
CRYMPPP1CAbhf-ucl25593058 details