Entity Details

Primary name S1PR1
Entity type gene
Source Source Link

Details

PrimaryID1901
RefseqGeneNG_016181
SymbolS1PR1
Namesphingosine-1-phosphate receptor 1
Chromosome1
Location1p21.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-05-15
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsS1PR1_HUMAN

GO terms

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GOName
GO:0001525 angiogenesis
GO:0001664 G protein-coupled receptor binding
GO:0001955 blood vessel maturation
GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis
GO:0003376 sphingosine-1-phosphate receptor signaling pathway
GO:0004930 G protein-coupled receptor activity
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005886 plasma membrane
GO:0006935 chemotaxis
GO:0007155 cell adhesion
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO:0007420 brain development
GO:0009897 external side of plasma membrane
GO:0016021 integral component of membrane
GO:0016477 cell migration
GO:0019221 cytokine-mediated signaling pathway
GO:0019222 regulation of metabolic process
GO:0019226 transmission of nerve impulse
GO:0030032 lamellipodium assembly
GO:0030155 regulation of cell adhesion
GO:0030182 neuron differentiation
GO:0030335 positive regulation of cell migration
GO:0030500 regulation of bone mineralization
GO:0030595 leukocyte chemotaxis
GO:0031226 intrinsic component of plasma membrane
GO:0031532 actin cytoskeleton reorganization
GO:0038036 sphingosine-1-phosphate receptor activity
GO:0043231 intracellular membrane-bounded organelle
GO:0043547 positive regulation of GTPase activity
GO:0045121 membrane raft
GO:0045124 regulation of bone resorption
GO:0045446 endothelial cell differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046625 sphingolipid binding
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0050927 positive regulation of positive chemotaxis
GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
GO:0051497 negative regulation of stress fiber assembly
GO:0061384 heart trabecula morphogenesis
GO:0072678 T cell migration

Diseases

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Interactions

34 interactions

InteractorPartnerSourcesPublicationsLink
S1PR1CMSS1BioGRID, IntAct21988832 details
S1PR1GNAI3BioGRID, HPRD8626678 details
S1PR1GNAI1BioGRID, HPRD8626678 details
S1PR1APPBioGRID21244100 details
S1PR1SP1IntAct20195357 details
S1PR1S1PR2IntAct24851274 details
S1PR1CD69DIP16525420 details
S1PR1HTR1ABioGRID, HPRD11854302 details
S1PR1HTR1DBioGRID, HPRD11854302 details
S1PR1CAV1BioGRID, HPRD10921915 details
S1PR1PDGFRBBioGRID, HPRD12480944 details
S1PR1TRIP6BioGRID19293149 details
S1PR1WWP2BioGRID21555855 details
S1PR1AKT1HPRD11583630 details
S1PR1CLEC2DBioGRID, IntAct28514442 details
S1PR1GOLPH3LBioGRID, IntAct28514442 details
S1PR1TTYH3BioGRID, IntAct28514442 details
S1PR1LMBR1BioGRID, IntAct28514442 details
S1PR1ARL10BioGRID, IntAct28514442 details
S1PR1GPRIN1BioGRID, IntAct28514442 details
S1PR1ATP2B3BioGRID, IntAct28514442 details
S1PR1GNA13BioGRID, IntAct28514442 details
S1PR1CD47BioGRID, IntAct28514442 details
S1PR1GNG5BioGRID, IntAct28514442 details
S1PR1ATP12ABioGRID, IntAct28514442 details
S1PR1HK3BioGRID, IntAct28514442 details
S1PR1GNAQBioGRID, IntAct28514442 details
S1PR1ATP1A3BioGRID, IntAct28514442 details
S1PR1SRCBioGRID, IntAct28514442 details
S1PR1ACP2BioGRID, IntAct28514442 details
S1PR1RAP2ABioGRID, IntAct28514442 details
S1PR1HRASBioGRID, IntAct28514442 details
S1PR1POTEFBioGRID, IntAct28514442 details
S1PR1MKRN2BioGRID32460013 details