Entity Details

Primary name PKP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13835
EntryNamePKP1_HUMAN
FullNamePlakophilin-1
TaxID9606
Evidenceevidence at protein level
Length747
SequenceStatuscomplete
DateCreated2002-01-23
DateModified2021-06-02

Ontological Relatives

GenesPKP1

GO terms

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GOName
GO:0001533 cornified envelope
GO:0005521 lamin binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005882 intermediate filament
GO:0005886 plasma membrane
GO:0005912 adherens junction
GO:0007043 cell-cell junction assembly
GO:0007155 cell adhesion
GO:0007165 signal transduction
GO:0010628 positive regulation of gene expression
GO:0019215 intermediate filament binding
GO:0030057 desmosome
GO:0030280 structural constituent of skin epidermis
GO:0031424 keratinization
GO:0043312 neutrophil degranulation
GO:0045110 intermediate filament bundle assembly
GO:0045296 cadherin binding
GO:0070268 cornification
GO:0098609 cell-cell adhesion
GO:0101003 ficolin-1-rich granule membrane
GO:1902373 negative regulation of mRNA catabolic process
GO:1990124 messenger ribonucleoprotein complex

Subcellular Location

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Subcellular Location
Cell junction
Nucleus

Domains

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DomainNameCategoryType
IPR000225 ArmadilloRepeatRepeat
IPR011989 Armadillo-like helicalFamilyHomologous superfamily
IPR016024 Armadillo-type foldFamilyHomologous superfamily
IPR028432 Plakophilin-1FamilyFamily
IPR028435 Plakophilin/Delta cateninFamilyFamily

Diseases

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