Entity Details

Primary name EPHB2
Entity type gene
Source Source Link

Details

PrimaryID2048
RefseqGeneNG_011804
SymbolEPHB2
NameEPH receptor B2
Chromosome1
Location1p36.12
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-20
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsEPHB2_HUMAN

GO terms

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GOName
GO:0001525 angiogenesis
GO:0001540 amyloid-beta binding
GO:0001655 urogenital system development
GO:0001933 negative regulation of protein phosphorylation
GO:0002639 positive regulation of immunoglobulin production
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005005 transmembrane-ephrin receptor activity
GO:0005102 signaling receptor binding
GO:0005524 ATP binding
GO:0005576 extracellular region
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007162 negative regulation of cell adhesion
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007275 multicellular organism development
GO:0007399 nervous system development
GO:0007411 axon guidance
GO:0007413 axonal fasciculation
GO:0007611 learning or memory
GO:0007612 learning
GO:0008046 axon guidance receptor activity
GO:0010628 positive regulation of gene expression
GO:0016310 phosphorylation
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0021631 optic nerve morphogenesis
GO:0021952 central nervous system projection neuron axonogenesis
GO:0022038 corpus callosum development
GO:0030193 regulation of blood coagulation
GO:0030335 positive regulation of cell migration
GO:0030424 axon
GO:0030425 dendrite
GO:0030890 positive regulation of B cell proliferation
GO:0031290 retinal ganglion cell axon guidance
GO:0031915 positive regulation of synaptic plasticity
GO:0032760 positive regulation of tumor necrosis factor production
GO:0033674 positive regulation of kinase activity
GO:0042113 B cell activation
GO:0042472 inner ear morphogenesis
GO:0042802 identical protein binding
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043235 receptor complex
GO:0044877 protein-containing complex binding
GO:0046580 negative regulation of Ras protein signal transduction
GO:0048013 ephrin receptor signaling pathway
GO:0048168 regulation of neuronal synaptic plasticity
GO:0048170 positive regulation of long-term neuronal synaptic plasticity
GO:0048593 camera-type eye morphogenesis
GO:0050771 negative regulation of axonogenesis
GO:0050878 regulation of body fluid levels
GO:0051389 obsolete inactivation of MAPKK activity
GO:0051965 positive regulation of synapse assembly
GO:0060021 roof of mouth development
GO:0060996 dendritic spine development
GO:0060997 dendritic spine morphogenesis
GO:0070373 negative regulation of ERK1 and ERK2 cascade
GO:0071679 commissural neuron axon guidance
GO:0097104 postsynaptic membrane assembly
GO:0098794 postsynapse
GO:0098978 glutamatergic synapse
GO:0099055 integral component of postsynaptic membrane
GO:0099056 integral component of presynaptic membrane
GO:0099557 trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission
GO:0106028 neuron projection retraction
GO:1900273 positive regulation of long-term synaptic potentiation
GO:1903078 positive regulation of protein localization to plasma membrane
GO:1904782 negative regulation of NMDA glutamate receptor activity
GO:1904783 positive regulation of NMDA glutamate receptor activity

Diseases

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Interactions

65 interactions

InteractorPartnerSourcesPublicationsLink
EPHB2AFDNBioGRID, MINT9707552 details
EPHB2NUP153MINT17255949 details
EPHB2EFNB2BioGRID, HPRD, IntAct11780069 26186194 28514442 details
EPHB2MTMR14BioGRID, MINT28065597 details
EPHB2TRIM54BioGRID, IntAct31391242 details
EPHB2COMTIntAct32814053 details
EPHB2PHYHIntAct32814053 details
EPHB2CLN6IntAct32814053 details
EPHB2JPH3IntAct32814053 details
EPHB2SPRED1IntAct32814053 details
EPHB2TARDBPIntAct32814053 details
EPHB2SRCBioGRID, HPRD10644995 18713744 9632142 details
EPHB2RASA1BioGRID, HPRD10644995 9233798 details
EPHB2CRKBioGRID10644995 details
EPHB2EPHB2BioGRID, HPRD10572014 17192257 18797457 9233798 9632142 9933164 details
EPHB2YES1BioGRID9632142 details
EPHB2PLCG1BioGRID9632142 details
EPHB2ABL1BioGRID, HPRD11494128 details
EPHB2ABL2BioGRID, HPRD11494128 details
EPHB2FBXO7BioGRID27503909 details
EPHB2ERBB2BioGRID30898150 details
EPHB2SDCBPHPRD9883737 details
EPHB2PICK1HPRD10839360 9883737 details
EPHB2RBL1IntAct17353931 details
EPHB2PTP4A2IntAct17353931 details
EPHB2MAPK14MINT17255949 details
EPHB2ACP1BioGRID, HPRD9499402 details
EPHB2RYKBioGRID, HPRD11956217 details
EPHB2ITSN1BioGRID, HPRD12389031 details
EPHB2ALKBioGRID14968112 details
EPHB2HMMRBioGRID22610405 details
EPHB2SPSB4BioGRID28931592 details
EPHB2SPSB1BioGRID28931592 details
EPHB2GRIN1BioGRID, HPRD11754835 22544902 details
EPHB2RRASHPRD10570155 details
EPHB2EFNB1HPRD8878483 details
EPHB2NCK1HPRD9233798 details
EPHB2ERFHPRD10330152 details
EPHB2EFNA5HPRD15107857 details
EPHB2SYNJ1HPRD15821731 details
EPHB2SH2D3CHPRD10542222 details
EPHB2GRIN2BHPRD11799243 details
EPHB2SDC2HPRD11580899 details
EPHB2VAV2HPRD15848800 details
EPHB2KALRNHPRD12546821 details
EPHB2ARHGEF6HPRD10523848 details
EPHB2GRB2HPRD16298995 details
EPHB2VEGFAHPRD17318185 details
EPHB2KSR1HPRD11940661 details
EPHB2MMP2HPRD18713744 details
EPHB2MMP9HPRD18713744 details
EPHB2FOSHPRD12972619 7816602 details
EPHB2SPSB2BioGRID, IntAct26186194 28514442 details
EPHB2TSPAN15UniProt26686862 details
EPHB2KDM4ABioGRID26344197 details
EPHB2RNF4BioGRID29180619 details
EPHB2KIF23BioGRID31586073 details
EPHB2ARF6BioGRID34079125 details
EPHB2CAV1BioGRID34079125 details
EPHB2KRASBioGRID34079125 details
EPHB2RAB2ABioGRID34079125 details
EPHB2RAB35BioGRID34079125 details
EPHB2RHOBBioGRID34079125 details
EPHB2VIRMABioGRID29507755 details
EPHB2HNRNPH1BioGRID26760575 details