Entity Details

Primary name FBN1
Entity type gene
Source Source Link

Details

PrimaryID2200
RefseqGeneNG_008805
SymbolFBN1
Namefibrillin 1
Chromosome15
Location15q21.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1992-10-07
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsFBN1_HUMAN

GO terms

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GOName
GO:0001501 skeletal system development
GO:0001527 microfibril
GO:0001656 metanephros development
GO:0005178 integrin binding
GO:0005179 hormone activity
GO:0005201 extracellular matrix structural constituent
GO:0005509 calcium ion binding
GO:0005576 extracellular region
GO:0005604 basement membrane
GO:0005615 extracellular space
GO:0005788 endoplasmic reticulum lumen
GO:0006006 glucose metabolic process
GO:0007507 heart development
GO:0008201 heparin binding
GO:0009653 anatomical structure morphogenesis
GO:0010737 protein kinase A signaling
GO:0030023 extracellular matrix constituent conferring elasticity
GO:0030198 extracellular matrix organization
GO:0031012 extracellular matrix
GO:0033627 cell adhesion mediated by integrin
GO:0034199 activation of protein kinase A activity
GO:0035582 sequestering of BMP in extracellular matrix
GO:0035583 sequestering of TGFbeta in extracellular matrix
GO:0042593 glucose homeostasis
GO:0042802 identical protein binding
GO:0043010 camera-type eye development
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
GO:0044877 protein-containing complex binding
GO:0045671 negative regulation of osteoclast differentiation
GO:0048048 embryonic eye morphogenesis
GO:0048050 post-embryonic eye morphogenesis
GO:0062023 collagen-containing extracellular matrix
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:1990314 cellular response to insulin-like growth factor stimulus
GO:2001205 negative regulation of osteoclast development

Diseases

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